Resource reallocation under persistent immune activation drives trade-offs between life history and immunity in pirk-deficient Musca domestica

Resource reallocation under persistent immune activation drives trade-offs between life history and immunity in pirk-deficient Musca domestica

Abstract Background The activation of the immune system by pathogens imposes significant energetic costs on hosts, which may result in the diversion of resources away from other non-essential biological processes, such as growth and reproduction. The underlying mechanisms of trade-offs between immun...

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Bibliographic Details
Main Authors: Ting Tang, Lan Yang, Liya Ma, Yu Ren, Mengnan Li, Shufan Guo, Xin Wang, Yuming Zhang, Fengsong Liu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Musca domestica
Immune regulation
Energy metabolism
Trade-off
Pirk
Online Access:https://doi.org/10.1186/s12915-025-02324-6
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