A Role for Exocytosis in the Spatial Regulationof Actin Organization
The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role i...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2003-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2003.119 |
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| _version_ | 1850215380988985344 |
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| author | Xiang-Dong Gao Stefan Albert |
| author_facet | Xiang-Dong Gao Stefan Albert |
| author_sort | Xiang-Dong Gao |
| collection | DOAJ |
| description | The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other. |
| format | Article |
| id | doaj-art-802ac93e1f1a437cb3f0eb49fcf03b8c |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-802ac93e1f1a437cb3f0eb49fcf03b8c2025-08-20T02:08:38ZengWileyThe Scientific World Journal1537-744X2003-01-0131359136210.1100/tsw.2003.119A Role for Exocytosis in the Spatial Regulationof Actin OrganizationXiang-Dong Gao0Stefan Albert1Department of Cell and Developmental Biology, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104-6058, USADepartment of Cell and Developmental Biology, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104-6058, USAThe efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other.http://dx.doi.org/10.1100/tsw.2003.119 |
| spellingShingle | Xiang-Dong Gao Stefan Albert A Role for Exocytosis in the Spatial Regulationof Actin Organization The Scientific World Journal |
| title | A Role for Exocytosis in the Spatial Regulationof Actin Organization |
| title_full | A Role for Exocytosis in the Spatial Regulationof Actin Organization |
| title_fullStr | A Role for Exocytosis in the Spatial Regulationof Actin Organization |
| title_full_unstemmed | A Role for Exocytosis in the Spatial Regulationof Actin Organization |
| title_short | A Role for Exocytosis in the Spatial Regulationof Actin Organization |
| title_sort | role for exocytosis in the spatial regulationof actin organization |
| url | http://dx.doi.org/10.1100/tsw.2003.119 |
| work_keys_str_mv | AT xiangdonggao aroleforexocytosisinthespatialregulationofactinorganization AT stefanalbert aroleforexocytosisinthespatialregulationofactinorganization AT xiangdonggao roleforexocytosisinthespatialregulationofactinorganization AT stefanalbert roleforexocytosisinthespatialregulationofactinorganization |