Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19
Background: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition that predisposes patients to severe complications when infected with SARS-CoV-2 (COVID-19). Hematological alterations, particularly in erythrocyte levels, may influence the clinical course and outcomes in...
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Indonesian Society for Biochemistry and Molecular Biology
2025-02-01
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| Series: | Acta Biochimica Indonesiana |
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| Online Access: | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/198 |
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| author | Siti Nur Chasanah Aslani Thereestiana Sari Djamila Zakaria Ayutia Safira Rusidana Thalib |
| author_facet | Siti Nur Chasanah Aslani Thereestiana Sari Djamila Zakaria Ayutia Safira Rusidana Thalib |
| author_sort | Siti Nur Chasanah |
| collection | DOAJ |
| description |
Background: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition that predisposes patients to severe complications when infected with SARS-CoV-2 (COVID-19). Hematological alterations, particularly in erythrocyte levels, may influence the clinical course and outcomes in these high-risk individuals. Objective: This study aimed to evaluate the erythrocyte profile of COPD patients with and without COVID-19 at RS Paru Dr. Ario Wirawan Salatiga.
Methods: An analytic study design was employed. Participants were recruited using consecutive sampling. All COPD patients admitted between March 2019 and December 2023 were included. A total of 53 COPD patients participated, comprising 27 COVID-19-positive and 26 COVID-19-negative patients.
Results: The mean erythrocyte level in the COVID-19-positive COPD group was 4.23 ± 0.73 million/µl, while in the COVID-19-negative COPD group, it was 4.77 ± 0.78 million/µl. Although a statistically significant difference was observed between the two groups (p = 0.012), both values remain within the normal reference range.
Conclusion: Erythrocyte levels in both the COVID-19-positive and COVID-19-negative COPD groups remained within the normal range, although the levels were relatively lower in the COVID-19-positive group with statistical significance. Further research is needed to explore the underlying mechanisms contributing to this difference.
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| format | Article |
| id | doaj-art-80184f83d6504cecae06924c25a796aa |
| institution | Kabale University |
| issn | 2654-6108 2654-3222 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Indonesian Society for Biochemistry and Molecular Biology |
| record_format | Article |
| series | Acta Biochimica Indonesiana |
| spelling | doaj-art-80184f83d6504cecae06924c25a796aa2025-02-08T03:04:38ZengIndonesian Society for Biochemistry and Molecular BiologyActa Biochimica Indonesiana2654-61082654-32222025-02-018110.32889/actabiona.198Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19Siti Nur Chasanah0Aslani Thereestiana Sari1Djamila Zakaria2Ayutia Safira Rusidana Thalib3Biochemistry Departement Medical Faculty, Universitas Wahid HasyimInternal Medicine Department Medical Faculty, Universitas Wahid HasyimPatophysiology Departement Medical Faculty, Universitas Wahid HasyimBachelor degree Medical Faculty, Universitas Wahid Hasyim Background: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition that predisposes patients to severe complications when infected with SARS-CoV-2 (COVID-19). Hematological alterations, particularly in erythrocyte levels, may influence the clinical course and outcomes in these high-risk individuals. Objective: This study aimed to evaluate the erythrocyte profile of COPD patients with and without COVID-19 at RS Paru Dr. Ario Wirawan Salatiga. Methods: An analytic study design was employed. Participants were recruited using consecutive sampling. All COPD patients admitted between March 2019 and December 2023 were included. A total of 53 COPD patients participated, comprising 27 COVID-19-positive and 26 COVID-19-negative patients. Results: The mean erythrocyte level in the COVID-19-positive COPD group was 4.23 ± 0.73 million/µl, while in the COVID-19-negative COPD group, it was 4.77 ± 0.78 million/µl. Although a statistically significant difference was observed between the two groups (p = 0.012), both values remain within the normal reference range. Conclusion: Erythrocyte levels in both the COVID-19-positive and COVID-19-negative COPD groups remained within the normal range, although the levels were relatively lower in the COVID-19-positive group with statistical significance. Further research is needed to explore the underlying mechanisms contributing to this difference. https://pbbmi.org/newjurnal/index.php/actabioina/article/view/198COPDCOVID-19Erythrocyte count |
| spellingShingle | Siti Nur Chasanah Aslani Thereestiana Sari Djamila Zakaria Ayutia Safira Rusidana Thalib Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 Acta Biochimica Indonesiana COPD COVID-19 Erythrocyte count |
| title | Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 |
| title_full | Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 |
| title_fullStr | Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 |
| title_full_unstemmed | Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 |
| title_short | Erythrocyte levels in chronic obstructive pulmonary disease (COPD) patients with a history of positive and negative COVID-19 |
| title_sort | erythrocyte levels in chronic obstructive pulmonary disease copd patients with a history of positive and negative covid 19 |
| topic | COPD COVID-19 Erythrocyte count |
| url | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/198 |
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