An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data

ABSTRACT Introduction We aim to assess HPV vaccine administration among privately insured populations before and during the COVID‐19 pandemic in the United States and stratify the assessments by demographic and geographic characteristics. Methods Using the Merative MarketScan Commercial Claims and E...

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Main Authors: Milkie Vu, Jingjing Li, Kai Hong, Jennifer W. Kaminski, Bo‐Hyun Cho, Yoonjae Kang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Online Access:https://doi.org/10.1002/cam4.70761
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author Milkie Vu
Jingjing Li
Kai Hong
Jennifer W. Kaminski
Bo‐Hyun Cho
Yoonjae Kang
author_facet Milkie Vu
Jingjing Li
Kai Hong
Jennifer W. Kaminski
Bo‐Hyun Cho
Yoonjae Kang
author_sort Milkie Vu
collection DOAJ
description ABSTRACT Introduction We aim to assess HPV vaccine administration among privately insured populations before and during the COVID‐19 pandemic in the United States and stratify the assessments by demographic and geographic characteristics. Methods Using the Merative MarketScan Commercial Claims and Encounters Database, we estimated monthly and yearly HPV vaccine administration among people aged 9–26 from 2019 to 2022, measured as the proportion of the enrolled population who received ≥ 1 dose of HPV vaccine during that month or year, and their relative percent change from 2020 to 2022, compared to the same period in 2019, overall and stratified by age group, sex, and urbanicity. Results HPV vaccine administration in 2020, 2021, and 2022 was lower than in 2019 and continued to decline for all age groups. The relative percent change in rate in 2022 relative to 2019 was −6.0% among children, −38.3% among adolescents, and −42.5% among young adults. The patterns were similar across subgroups, with certain disparities in magnitude. By subpopulations, the highest percent declines in 2022 relative to 2019 in each age group were observed among children in rural areas (−13.5%), male adolescents (−39.8%), and young adults in rural areas (−46.0%). Conclusion During the COVID‐19 pandemic, HPV vaccine administration dropped substantially and had not exceeded the pre‐pandemic levels by the end of 2022, with larger declines seen among male adolescents and young adults in rural areas. Our results highlight the need for continuing monitoring and targeted intervention strategies to improve HPV vaccine administration.
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spelling doaj-art-800d4606348b43dc94d214d48c67e8882025-08-20T03:10:40ZengWileyCancer Medicine2045-76342025-03-01146n/an/a10.1002/cam4.70761An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims DataMilkie Vu0Jingjing Li1Kai Hong2Jennifer W. Kaminski3Bo‐Hyun Cho4Yoonjae Kang5Department of Preventive Medicine, Feinberg School of Medicine Northwestern University Chicago Illinois USADepartment of Behavior, Social, and Health Education Sciences, Rollins School of Public Health Emory University Atlanta Georgia USAOffice of Policy, Performance, and Evaluation Centers for Disease Control and Prevention Atlanta Georgia USAOffice of Policy, Performance, and Evaluation Centers for Disease Control and Prevention Atlanta Georgia USAThe National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention Atlanta Georgia USAThe National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention Atlanta Georgia USAABSTRACT Introduction We aim to assess HPV vaccine administration among privately insured populations before and during the COVID‐19 pandemic in the United States and stratify the assessments by demographic and geographic characteristics. Methods Using the Merative MarketScan Commercial Claims and Encounters Database, we estimated monthly and yearly HPV vaccine administration among people aged 9–26 from 2019 to 2022, measured as the proportion of the enrolled population who received ≥ 1 dose of HPV vaccine during that month or year, and their relative percent change from 2020 to 2022, compared to the same period in 2019, overall and stratified by age group, sex, and urbanicity. Results HPV vaccine administration in 2020, 2021, and 2022 was lower than in 2019 and continued to decline for all age groups. The relative percent change in rate in 2022 relative to 2019 was −6.0% among children, −38.3% among adolescents, and −42.5% among young adults. The patterns were similar across subgroups, with certain disparities in magnitude. By subpopulations, the highest percent declines in 2022 relative to 2019 in each age group were observed among children in rural areas (−13.5%), male adolescents (−39.8%), and young adults in rural areas (−46.0%). Conclusion During the COVID‐19 pandemic, HPV vaccine administration dropped substantially and had not exceeded the pre‐pandemic levels by the end of 2022, with larger declines seen among male adolescents and young adults in rural areas. Our results highlight the need for continuing monitoring and targeted intervention strategies to improve HPV vaccine administration.https://doi.org/10.1002/cam4.70761
spellingShingle Milkie Vu
Jingjing Li
Kai Hong
Jennifer W. Kaminski
Bo‐Hyun Cho
Yoonjae Kang
An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
Cancer Medicine
title An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
title_full An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
title_fullStr An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
title_full_unstemmed An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
title_short An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID‐19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data
title_sort ecological analysis of hpv vaccination in the united states before and during the covid 19 pandemic by age sex and urbanicity using private insurance claims data
url https://doi.org/10.1002/cam4.70761
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