Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC

Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC

Several oxylipins including hydroxy-PUFAs act as lipid mediators. In biological samples, the major part occurs esterified in glycero-phospholipids (PLs) or other lipids. In this work, the incorporation into glycero-PLs of 15-hydroxyeicosatetraenoic acid (15(S)-HETE), 15(S)-hydroxyeicosapentaenoic ac...

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Bibliographic Details
Main Authors: Laura Carpanedo, Luca M. Wende, Bjarne Goebel, Ann-Kathrin Häfner, Michel André Chromik, Nadja Kampschulte, Dieter Steinhilber, Nils Helge Schebb
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Lipid Research
Subjects:
oxidized lipids
lipidomics
cell signaling
inflammation
arachidonic acid
oxylipin incorporation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227525001014
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