γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control.
Stable microbial colonization of the skin depends on tight control by the host immune system. The lipid-dependent yeast Malassezia typically colonizes skin as a harmless commensal and is subject to host type 17 immunosurveillance, but this fungus has also been associated with diverse skin pathologie...
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| Main Authors: | Fiorella Ruchti, Meret Tuor, Liya Mathew, Neil E McCarthy, Salomé LeibundGut-Landmann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011668&type=printable |
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