Incidence of Gastric Cancer in Patients with Laryngeal Cancer

Background/Aims: Gastric cancer (GC) is the second most common cancer in Korea and the most common in men in the south of the country. We investigated the incidence of synchronous GC in patients with head and neck squamous cell carcinoma (HNSCC) in the southern part of Korea. Materials and Methods:...

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Main Authors: Ji-Hyun Seo, Hyun-Jin Kim, Jung Je Park, Ok-Jae Lee, Jin Pyeong Kim, Seong-Ki Ahn, Jeong Seok Hwa, Jong Sil Lee, Hee-Shang Youn
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2017-12-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.190
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author Ji-Hyun Seo
Hyun-Jin Kim
Jung Je Park
Ok-Jae Lee
Jin Pyeong Kim
Seong-Ki Ahn
Jeong Seok Hwa
Jong Sil Lee
Hee-Shang Youn
author_facet Ji-Hyun Seo
Hyun-Jin Kim
Jung Je Park
Ok-Jae Lee
Jin Pyeong Kim
Seong-Ki Ahn
Jeong Seok Hwa
Jong Sil Lee
Hee-Shang Youn
author_sort Ji-Hyun Seo
collection DOAJ
description Background/Aims: Gastric cancer (GC) is the second most common cancer in Korea and the most common in men in the south of the country. We investigated the incidence of synchronous GC in patients with head and neck squamous cell carcinoma (HNSCC) in the southern part of Korea. Materials and Methods: We retrospectively reviewed the medical records of HNSCC patients treated between 2011 and 2014. In patients with synchronous GC, evaluation included a history of smoking and alcohol consumption, endoscopic findings, Campylobacter-like organism (CLO) test, and immunohistochemical analysis of preserved HNSCC tissues. Results: Analysis of the records of 153 HNSCC patients revealed tumors of the larynx in 56 patients (36.6%), of the pharynx in 74 patients (48.4%), and tumors at other locations in 23 patients (15.0%). The mean age of patients was 66.0 years, and the men:women ratio was 8:1. Synchronous cancers were detected in 12 patients. We observed esophageal squamous cell carcinoma (SCC) in five patients (3.3%), and gastric adenocarcinoma in seven patients (4.6%). Synchronous GC was detected in patients with laryngeal SCC. All cases of GC were classified as early GC. Conclusions: Synchronous GC was as frequent as esophageal SCC in patients with HNSCC, and all cases of GC were observed to be early stage cancers in this study. Thorough endoscopic examination should be performed in patients with laryngeal cancer to detect the presence of synchronous GC.
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publisher Korean College of Helicobacter and Upper Gastrointestinal Research
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spelling doaj-art-7ff4a1d0a4d943b1a3dcac51b293cdfb2025-08-20T03:14:58ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-12-0117419019410.7704/kjhugr.2017.17.4.190kjhugr.2017.17.4.190Incidence of Gastric Cancer in Patients with Laryngeal CancerJi-Hyun Seo0Hyun-Jin Kim1Jung Je Park2Ok-Jae Lee3Jin Pyeong Kim4Seong-Ki Ahn5Jeong Seok Hwa6Jong Sil Lee7Hee-Shang Youn8Department of Pediatrics, Gyeongsang National University School of Medicine, Jinju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, KoreaGyeongsang Institute of Sciences, Gyeongsang National University School of Medicine, Jinju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, KoreaGyeongsang Institute of Sciences, Gyeongsang National University School of Medicine, Jinju, KoreaGyeongsang Institute of Sciences, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Urology, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pathology, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics, Gyeongsang National University School of Medicine, Jinju, KoreaBackground/Aims: Gastric cancer (GC) is the second most common cancer in Korea and the most common in men in the south of the country. We investigated the incidence of synchronous GC in patients with head and neck squamous cell carcinoma (HNSCC) in the southern part of Korea. Materials and Methods: We retrospectively reviewed the medical records of HNSCC patients treated between 2011 and 2014. In patients with synchronous GC, evaluation included a history of smoking and alcohol consumption, endoscopic findings, Campylobacter-like organism (CLO) test, and immunohistochemical analysis of preserved HNSCC tissues. Results: Analysis of the records of 153 HNSCC patients revealed tumors of the larynx in 56 patients (36.6%), of the pharynx in 74 patients (48.4%), and tumors at other locations in 23 patients (15.0%). The mean age of patients was 66.0 years, and the men:women ratio was 8:1. Synchronous cancers were detected in 12 patients. We observed esophageal squamous cell carcinoma (SCC) in five patients (3.3%), and gastric adenocarcinoma in seven patients (4.6%). Synchronous GC was detected in patients with laryngeal SCC. All cases of GC were classified as early GC. Conclusions: Synchronous GC was as frequent as esophageal SCC in patients with HNSCC, and all cases of GC were observed to be early stage cancers in this study. Thorough endoscopic examination should be performed in patients with laryngeal cancer to detect the presence of synchronous GC.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.190Gastric cancerLaryngeal cancerSecond primary neoplasm
spellingShingle Ji-Hyun Seo
Hyun-Jin Kim
Jung Je Park
Ok-Jae Lee
Jin Pyeong Kim
Seong-Ki Ahn
Jeong Seok Hwa
Jong Sil Lee
Hee-Shang Youn
Incidence of Gastric Cancer in Patients with Laryngeal Cancer
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Gastric cancer
Laryngeal cancer
Second primary neoplasm
title Incidence of Gastric Cancer in Patients with Laryngeal Cancer
title_full Incidence of Gastric Cancer in Patients with Laryngeal Cancer
title_fullStr Incidence of Gastric Cancer in Patients with Laryngeal Cancer
title_full_unstemmed Incidence of Gastric Cancer in Patients with Laryngeal Cancer
title_short Incidence of Gastric Cancer in Patients with Laryngeal Cancer
title_sort incidence of gastric cancer in patients with laryngeal cancer
topic Gastric cancer
Laryngeal cancer
Second primary neoplasm
url http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.190
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