A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure

McLeod’s syndrome (MLS) is an X-linked disorder caused by mutations in the XK gene with neurological manifestations as well as cardiomyopathy. This is a case of acute exacerbation of heart failure in a 44-year-old White male with a confirmed diagnosis of MLS, which was managed with guideline-directe...

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Main Authors: Hemanth K. Boppana, Samarthkumar Thakkar, Harsh P. Patel, Rody G. Bou Chaaya, Scott Feitell
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2023-09-01
Series:Methodist DeBakey Cardiovascular Journal
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Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1164
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author Hemanth K. Boppana
Samarthkumar Thakkar
Harsh P. Patel
Rody G. Bou Chaaya
Scott Feitell
author_facet Hemanth K. Boppana
Samarthkumar Thakkar
Harsh P. Patel
Rody G. Bou Chaaya
Scott Feitell
author_sort Hemanth K. Boppana
collection DOAJ
description McLeod’s syndrome (MLS) is an X-linked disorder caused by mutations in the XK gene with neurological manifestations as well as cardiomyopathy. This is a case of acute exacerbation of heart failure in a 44-year-old White male with a confirmed diagnosis of MLS, which was managed with guideline-directed medical therapy and placement of an implantable cardioverter defibrillator with recovery in ejection fraction.
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institution Kabale University
issn 1947-6108
language English
publishDate 2023-09-01
publisher Houston Methodist DeBakey Heart & Vascular Center
record_format Article
series Methodist DeBakey Cardiovascular Journal
spelling doaj-art-7fe6961334c24e42a56f7adf4bbb40812025-08-20T03:25:50ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082023-09-01191757810.14797/mdcvj.11641141A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart FailureHemanth K. Boppana0https://orcid.org/0000-0002-7637-9999Samarthkumar Thakkar1https://orcid.org/0000-0001-9562-3443Harsh P. Patel2https://orcid.org/0000-0002-7223-0265Rody G. Bou Chaaya3https://orcid.org/0000-0003-1953-5956Scott Feitell4https://orcid.org/0000-0002-7809-6546Rochester General Hospital, Rochester, New YorkHouston Methodist DeBakey Heart & Vascular Center, Houston, TexasSouthern Illinois School of Medicine, Springfield, IllinoisHouston Methodist DeBakey Heart & Vascular Center, Houston, TexasSands Constellation Heart Institute, Rochester General Hospital, Rochester, NYMcLeod’s syndrome (MLS) is an X-linked disorder caused by mutations in the XK gene with neurological manifestations as well as cardiomyopathy. This is a case of acute exacerbation of heart failure in a 44-year-old White male with a confirmed diagnosis of MLS, which was managed with guideline-directed medical therapy and placement of an implantable cardioverter defibrillator with recovery in ejection fraction.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1164mcleod’s syndromeguideline-directed medical therapyimplantable cardioverter defibrillatorlate galodinium enhancement
spellingShingle Hemanth K. Boppana
Samarthkumar Thakkar
Harsh P. Patel
Rody G. Bou Chaaya
Scott Feitell
A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
Methodist DeBakey Cardiovascular Journal
mcleod’s syndrome
guideline-directed medical therapy
implantable cardioverter defibrillator
late galodinium enhancement
title A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
title_full A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
title_fullStr A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
title_full_unstemmed A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
title_short A Case of McLeod’s Syndrome Presenting with Severe Decompensated Heart Failure
title_sort case of mcleod s syndrome presenting with severe decompensated heart failure
topic mcleod’s syndrome
guideline-directed medical therapy
implantable cardioverter defibrillator
late galodinium enhancement
url https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1164
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