Cardiac organoids: a new tool for disease modeling and drug screening applications

Cardiac organoids: a new tool for disease modeling and drug screening applications

Cardiac organoid is a miniature and simplified three-dimensional (3D) cellular model system grown from progenitor cells or stem cells that more accurately mimic the significant biological characteristics and functions of the normal cardiac system than conventional two-dimensional (2D) models. With c...

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Bibliographic Details
Main Authors: Ahmed Yaqinuddin, Abdullah Jabri, Abdulaziz Mhannayeh, Bader Taftafa, Mohamed Alsharif, Tasnim Abbad, Jibran Khan, Abdulrahman Elsalti, Raja Chinnappan, Eman A. Alshehri, Alaa Alzhrani, Dalia A. Obeid, Iriya Fujitsuka, Mahmood Khan, Mati ur Rehman, Tanveer Ahmad Mir
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac organoids
3D culture
decellularized matrix
disease model
drug screening
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1537730/full
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