Acteoside ameliorates cerebral ischemia/reperfusion injury in MCAO rats as a natural plasma Kallikrein inhibitor from Osmanthus fragrans flower

Acteoside ameliorates cerebral ischemia/reperfusion injury in MCAO rats as a natural plasma Kallikrein inhibitor from Osmanthus fragrans flower

Abstract Acteoside is the potential bioactive component of Osmanthus fragrans flowers for treating stroke. However, the pharmacological actions, therapeutic targets and underlying mechanisms of acteoside in cerebral ischemia/reperfusion injury remain poorly understood. In this study, we investigated...

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Bibliographic Details
Main Authors: Hui-hao Wang, Kai-rui Feng, Ping Li, Zhi-Yong Wang, Li Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Acteoside
Osmanthus fragrans
Plasma Kallikrein
Middle cerebral artery occlusion rat model
Online Access:https://doi.org/10.1038/s41598-025-06553-1
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