The role of PRP in the healing of disc degeneration and the effect of local anesthetics on PRP

The role of PRP in the healing of disc degeneration and the effect of local anesthetics on PRP

AimThis study aimed to investigate the regenerative effects of PRP on an experimental rat model of disc degeneration using histological and biochemical parameters. Additionally, we evaluated whether ropivacaine, a local anesthetic commonly used in clinical practice, affects the efficacy of PRP.Metho...

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Bibliographic Details
Main Authors: Ahmet Mert, Ayse Ikinci Keles, Murat Aydin, Huseyin Serkan Erol, Osman Fikret Sonmez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
inflammation
intervertebral disc degeneration
local anesthesia
platelet-rich plasma
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1613148/full
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