Pyo-septic complications of severe necrotizing forms of acute pancreatitis

Purpose of the study. Develop an algorithm for the diagnosis and treatment of purulent-septic complications of severe necrotizing forms of acute pancreatitis. Materials and methods. 5400 patients with acute pancreatitis were treated. To determine the infected pancreatic necrosis, the blood calciu...

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Main Authors: N. N. Veligotsky, S. E. Arutyunov, M. V. Klymenko, K. A. Aleksanyan
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2019-09-01
Series:Сучасні медичні технології
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Online Access:https://zmapo-journal.com/index.php/journal/article/view/145
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author N. N. Veligotsky
S. E. Arutyunov
M. V. Klymenko
K. A. Aleksanyan
author_facet N. N. Veligotsky
S. E. Arutyunov
M. V. Klymenko
K. A. Aleksanyan
author_sort N. N. Veligotsky
collection DOAJ
description Purpose of the study. Develop an algorithm for the diagnosis and treatment of purulent-septic complications of severe necrotizing forms of acute pancreatitis. Materials and methods. 5400 patients with acute pancreatitis were treated. To determine the infected pancreatic necrosis, the blood calcium level, and blood procalcitonin were studied, and a fine-needle biopsy was performed. Surgical interventions were performed in 874 (16,2%) patients who underwent 1057 surgical interventions. Results. 782 minimally invasive interventions were performed in 645 patients: video laparoscopic – 608 (77,7%), puncture-draining (under ultrasound control) – 102 (13,0%), endoscopic – 38 (4,9%). The following purulent-septic complications of severe forms of acute pancreatitis were revealed: infected pancreatic necrosis in 189 (17,9%), infected peripancreonecrosis in 167 (15,8%), infected pseudocystin109(12,5%)patients.173(19,8%) singlestage operative interventions were performed, 56 (6,4%) open-stage multistage patients were performed, and extended necrsequestrectomy was performed. Among minimally invasive interventions, minilaparotomy and lumbotomy were performed in 34 (4,3%). Conclusion. The use of monitoring laboratory and instrumental methods of research in the diagnosis of severe forms of acute pancreatitis and its complications allows you to determine in time the degree and volume of necrotic lesions of the pancreas and develop surgical tactics.
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spelling doaj-art-7fdff96e80e94c08949941b8c1309da92025-08-20T02:52:02ZengZaporizhzhia State Medical and Pharmaceutical UniversityСучасні медичні технології2072-93672019-09-013(42)374010.34287/MMT.3(42).2019.9145Pyo-septic complications of severe necrotizing forms of acute pancreatitisN. N. Veligotsky0S. E. Arutyunov1M. V. Klymenko2K. A. Aleksanyan3Kharkiv Medical Academy of Post-graduate Education Kharkiv, UkraineKharkiv Medical Academy of Post-graduate Education Kharkiv, UkraineKharkiv Medical Academy of Post-graduate Education Kharkiv, UkraineKharkiv Medical Academy of Post-graduate Education Kharkiv, UkrainePurpose of the study. Develop an algorithm for the diagnosis and treatment of purulent-septic complications of severe necrotizing forms of acute pancreatitis. Materials and methods. 5400 patients with acute pancreatitis were treated. To determine the infected pancreatic necrosis, the blood calcium level, and blood procalcitonin were studied, and a fine-needle biopsy was performed. Surgical interventions were performed in 874 (16,2%) patients who underwent 1057 surgical interventions. Results. 782 minimally invasive interventions were performed in 645 patients: video laparoscopic – 608 (77,7%), puncture-draining (under ultrasound control) – 102 (13,0%), endoscopic – 38 (4,9%). The following purulent-septic complications of severe forms of acute pancreatitis were revealed: infected pancreatic necrosis in 189 (17,9%), infected peripancreonecrosis in 167 (15,8%), infected pseudocystin109(12,5%)patients.173(19,8%) singlestage operative interventions were performed, 56 (6,4%) open-stage multistage patients were performed, and extended necrsequestrectomy was performed. Among minimally invasive interventions, minilaparotomy and lumbotomy were performed in 34 (4,3%). Conclusion. The use of monitoring laboratory and instrumental methods of research in the diagnosis of severe forms of acute pancreatitis and its complications allows you to determine in time the degree and volume of necrotic lesions of the pancreas and develop surgical tactics.https://zmapo-journal.com/index.php/journal/article/view/145acute pancreatitispancreatonecrosispurulent-septic complications
spellingShingle N. N. Veligotsky
S. E. Arutyunov
M. V. Klymenko
K. A. Aleksanyan
Pyo-septic complications of severe necrotizing forms of acute pancreatitis
Сучасні медичні технології
acute pancreatitis
pancreatonecrosis
purulent-septic complications
title Pyo-septic complications of severe necrotizing forms of acute pancreatitis
title_full Pyo-septic complications of severe necrotizing forms of acute pancreatitis
title_fullStr Pyo-septic complications of severe necrotizing forms of acute pancreatitis
title_full_unstemmed Pyo-septic complications of severe necrotizing forms of acute pancreatitis
title_short Pyo-septic complications of severe necrotizing forms of acute pancreatitis
title_sort pyo septic complications of severe necrotizing forms of acute pancreatitis
topic acute pancreatitis
pancreatonecrosis
purulent-septic complications
url https://zmapo-journal.com/index.php/journal/article/view/145
work_keys_str_mv AT nnveligotsky pyosepticcomplicationsofseverenecrotizingformsofacutepancreatitis
AT searutyunov pyosepticcomplicationsofseverenecrotizingformsofacutepancreatitis
AT mvklymenko pyosepticcomplicationsofseverenecrotizingformsofacutepancreatitis
AT kaaleksanyan pyosepticcomplicationsofseverenecrotizingformsofacutepancreatitis