Pathological Effects of COVID-19 on Body Organs
The SARS-COV-2 virus is the cause of the 2020 pandemic that has infected and killed millions worldwide. While the upper respiratory tract cells are the primary targets of COVID-19, the virus can infiltrate other tissues and organs, leading to potentially serious complications. The new coronavirus...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pasteur Institute of Iran
2023-03-01
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| Series: | Journal of Medical Microbiology and Infectious Diseases |
| Subjects: | |
| Online Access: | https://jommid.pasteur.ac.ir/article-1-475-en.html |
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| Summary: | The SARS-COV-2 virus is the cause of the 2020 pandemic that has infected and
killed millions worldwide. While the upper respiratory tract cells are the primary
targets of COVID-19, the virus can infiltrate other tissues and organs, leading
to potentially serious complications. The new coronavirus primarily affects
angiotensin II receptor and cytokine pathways, which can result in acute
pulmonary inflammation, pulmonary edema, acute respiratory distress
syndrome, vascular endothelial dysfunction, pulmonary embolism in the lungs,
and cardiomyopathy, arrhythmia, heart failure, and intravenous thrombosis in
the heart. COVID-19 infection can be associated with gastrointestinal symptoms
such as diarrhea, vomiting, and abdominal pain. Also, reports of mild and
transient liver damage, polyneuropathy, encephalitis, stroke, acute renal failure,
hypocortisolism, and damage to the hypothalamus and pituitary system are
available. COVID-19 can also be associated with skin symptoms such as rash,
urticaria, maculopapular lesions, and vascular lesions such as chill blain,
petechiae purpura, and scalpopathy. This narrative review evaluates the
pathogenesis of novel coronavirus on body organs based on relevant published
papers and reference books. |
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| ISSN: | 2345-5349 2345-5330 |