A Simple and Sensitive HPLC-MS/MS Assay for the Quantitation of Blonanserin and N-Desethyl Blonanserin in Rat Plasma and Its Application to Pharmacokinetic Study

A Simple and Sensitive HPLC-MS/MS Assay for the Quantitation of Blonanserin and N-Desethyl Blonanserin in Rat Plasma and Its Application to Pharmacokinetic Study

A high-performance liquid chromatographic method coupled with triple quadrupole mass spectrometry (LC-MS/MS) for the analysis of blonanserin and its active metabolite, N-desethyl blonanserin, in rat plasma has been developed and validated. The biological samples were treated by simple direct protein...

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Bibliographic Details
Main Authors:	Shan-qing Huang, Xiao-lin Li, Zhan-zhang Wang, Hao-yang Lu, Tao Xiao, Xiao-jia Ni, Shu-jing Liu, Ming Zhang, De-wei Shang, Yu-guan Wen
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Journal of Analytical Methods in Chemistry
Online Access:	http://dx.doi.org/10.1155/2022/5914581
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