Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation

Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation

BackgroundBlood glucose (BG) dysregulation, including hyperglycemia, hypoglycemia and increased glycemic variability (GV), is common in septic patients and potentially associated with poor clinical outcomes. However, the prognostic value of early BG trajectories remains unclear. We intend to investi...

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Main Authors: Huan Ma, Xiayan Qian, Xiaodong Song, Rongjie Jiang, Jialin Li, Fang Xiao, Ruoxu Dou, Xiangdong Guan, Ka Yin Lui, Shuhe Li, Changjie Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
sepsis
blood glucose
1-year mortality
trajectory analysis
K-means clustering
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610519/full
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