Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China

To validate the prevalence and biodiversity of ticks and tick-borne pathogens in Chongqing, a total of 601 ticks were collected from dogs, cattle, and goats within the Ta-pa Mountain range in Chongqing, China. Five distinct tick species were identified, including <i>Ixodes ovatus</i> (1....

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Main Authors: Lijun Wang, Zhongqiu Teng, Li Wan, Wen Wang, Shan Yuan, Qingzhu Huang, Juan Huang, Na Zhao, Meijia Wang, Kun Cao, Hai Huang, Jianguo Xu, Yi Yuan, Tian Qin
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/13/11/948
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author Lijun Wang
Zhongqiu Teng
Li Wan
Wen Wang
Shan Yuan
Qingzhu Huang
Juan Huang
Na Zhao
Meijia Wang
Kun Cao
Hai Huang
Jianguo Xu
Yi Yuan
Tian Qin
author_facet Lijun Wang
Zhongqiu Teng
Li Wan
Wen Wang
Shan Yuan
Qingzhu Huang
Juan Huang
Na Zhao
Meijia Wang
Kun Cao
Hai Huang
Jianguo Xu
Yi Yuan
Tian Qin
author_sort Lijun Wang
collection DOAJ
description To validate the prevalence and biodiversity of ticks and tick-borne pathogens in Chongqing, a total of 601 ticks were collected from dogs, cattle, and goats within the Ta-pa Mountain range in Chongqing, China. Five distinct tick species were identified, including <i>Ixodes ovatus</i> (1.66%, 10/601), <i>I. acutitarsus</i> (0.50%, 3/601), <i>Haemaphysalis flava</i> (10.32%, 62/601), <i>Ha. hystricis</i> (9.82%, 59/601), and <i>Ha. longicornis</i> (77.70%, 467/601). A suit of semi-nest PCR and nest PCR primers were custom-synthesized for the detection of tick-borne pathogens. The analysis yielded positive results for 7.15% <i>Rickettsia</i> (<i>Candidatus</i> R. principis, <i>R. japonica</i>, and <i>R. raoultii</i>), 3.49% <i>Anaplasma</i> (<i>A. bovis</i> and <i>A. capra</i>), 1.16% <i>Ehrlichia</i>, 1.83% <i>Coxiella burnetii</i>, and 3.49% protozoa (<i>Theileria. capreoli</i>, <i>T. orientalis</i>, <i>T. luwenshuni</i>, and <i>Babesia</i> sp.) in ticks. Notably, Ca. R. principis was identified for the first time in <i>I. ovatus</i> and <i>Ha. longicornis</i>. These findings underscore the significant prevalence and diversity of ticks and their associated pathogens within the Chongqing Ta-pa Mountain region. This study accordingly provides an extensive dataset that contributes to the epidemiological understanding and disease prevention strategies for tick-borne illnesses in the local area.
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spelling doaj-art-7fcca5e86caa40fc989281f9607041462025-08-20T02:48:07ZengMDPI AGPathogens2076-08172024-10-01131194810.3390/pathogens13110948Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, ChinaLijun Wang0Zhongqiu Teng1Li Wan2Wen Wang3Shan Yuan4Qingzhu Huang5Juan Huang6Na Zhao7Meijia Wang8Kun Cao9Hai Huang10Jianguo Xu11Yi Yuan12Tian Qin13Chengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaChengkou County Center for Disease Control and Prevention, Chongqing 405900, ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaTo validate the prevalence and biodiversity of ticks and tick-borne pathogens in Chongqing, a total of 601 ticks were collected from dogs, cattle, and goats within the Ta-pa Mountain range in Chongqing, China. Five distinct tick species were identified, including <i>Ixodes ovatus</i> (1.66%, 10/601), <i>I. acutitarsus</i> (0.50%, 3/601), <i>Haemaphysalis flava</i> (10.32%, 62/601), <i>Ha. hystricis</i> (9.82%, 59/601), and <i>Ha. longicornis</i> (77.70%, 467/601). A suit of semi-nest PCR and nest PCR primers were custom-synthesized for the detection of tick-borne pathogens. The analysis yielded positive results for 7.15% <i>Rickettsia</i> (<i>Candidatus</i> R. principis, <i>R. japonica</i>, and <i>R. raoultii</i>), 3.49% <i>Anaplasma</i> (<i>A. bovis</i> and <i>A. capra</i>), 1.16% <i>Ehrlichia</i>, 1.83% <i>Coxiella burnetii</i>, and 3.49% protozoa (<i>Theileria. capreoli</i>, <i>T. orientalis</i>, <i>T. luwenshuni</i>, and <i>Babesia</i> sp.) in ticks. Notably, Ca. R. principis was identified for the first time in <i>I. ovatus</i> and <i>Ha. longicornis</i>. These findings underscore the significant prevalence and diversity of ticks and their associated pathogens within the Chongqing Ta-pa Mountain region. This study accordingly provides an extensive dataset that contributes to the epidemiological understanding and disease prevention strategies for tick-borne illnesses in the local area.https://www.mdpi.com/2076-0817/13/11/948tick<i>Rickettsia</i><i>Anaplasma</i><i>Ehrlichia</i><i>Coxiella burnetii</i><i>Babesia</i>
spellingShingle Lijun Wang
Zhongqiu Teng
Li Wan
Wen Wang
Shan Yuan
Qingzhu Huang
Juan Huang
Na Zhao
Meijia Wang
Kun Cao
Hai Huang
Jianguo Xu
Yi Yuan
Tian Qin
Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
Pathogens
tick
<i>Rickettsia</i>
<i>Anaplasma</i>
<i>Ehrlichia</i>
<i>Coxiella burnetii</i>
<i>Babesia</i>
title Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
title_full Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
title_fullStr Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
title_full_unstemmed Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
title_short Molecular Epidemiology of Ticks and Tick-Borne Pathogens in the Ta-Pa Mountain Area of Chongqing, China
title_sort molecular epidemiology of ticks and tick borne pathogens in the ta pa mountain area of chongqing china
topic tick
<i>Rickettsia</i>
<i>Anaplasma</i>
<i>Ehrlichia</i>
<i>Coxiella burnetii</i>
<i>Babesia</i>
url https://www.mdpi.com/2076-0817/13/11/948
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