Comparison of blood RNA extraction methods used for gene expression profiling in amyotrophic lateral sclerosis.

Comparison of blood RNA extraction methods used for gene expression profiling in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes death within a mean of 2-3 years from symptom onset. There is no diagnostic test and the delay from symptom onset to diagnosis averages 12 months. The identification of prognostic and diagnostic biomarkers in ALS would fa...

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Bibliographic Details
Main Authors: Nadhim Bayatti, Johnathan Cooper-Knock, Joanna J Bury, Matthew Wyles, Paul R Heath, Janine Kirby, Pamela J Shaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0087508&type=printable
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