Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit
A 35-year-old female patient with no previously documented allergies who was admitted for elective gynaecological surgery, developed rapid onset, severe anaphylaxis, with dyspnea and cardiovascular collapse, in the operating theatre after receiving routine IV cefazolin prior to induction of anesthes...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2020/5283279 |
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| _version_ | 1849409900358139904 |
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| author | Sayed Hafizi Christine Nadeau Mohamed Gazarin Emily Mulligan |
| author_facet | Sayed Hafizi Christine Nadeau Mohamed Gazarin Emily Mulligan |
| author_sort | Sayed Hafizi |
| collection | DOAJ |
| description | A 35-year-old female patient with no previously documented allergies who was admitted for elective gynaecological surgery, developed rapid onset, severe anaphylaxis, with dyspnea and cardiovascular collapse, in the operating theatre after receiving routine IV cefazolin prior to induction of anesthesia. She failed to improve with two doses of intramuscular epinephrine followed by two boluses of intravenous epinephrine, but responded to an epinephrine infusion. She was assessed by Internal Medicine and discharged home the following day. This event demonstrates the speed, severity, and profound hypotension in an allergic reaction from intravenous medication, challenges in managing anaphylaxis, and importance of prompt administration of epinephrine via IM route, followed by IV if necessary, in the OR. The case highlighted the inability to ascertain the causative agent through typical allergy testing. |
| format | Article |
| id | doaj-art-7fc295e404e346c1af4f483aaa298ec5 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-7fc295e404e346c1af4f483aaa298ec52025-08-20T03:35:20ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/52832795283279Refractory Unforeseen Anaphylaxis Case in a Rural OR UnitSayed Hafizi0Christine Nadeau1Mohamed Gazarin2Emily Mulligan3Winchester District Memorial Hospital, 566 Louise St, Winchester, ON, K0C 2K0, CanadaWinchester District Memorial Hospital, 566 Louise St, Winchester, ON, K0C 2K0, CanadaWinchester District Memorial Hospital, 566 Louise St, Winchester, ON, K0C 2K0, CanadaWinchester District Memorial Hospital, 566 Louise St, Winchester, ON, K0C 2K0, CanadaA 35-year-old female patient with no previously documented allergies who was admitted for elective gynaecological surgery, developed rapid onset, severe anaphylaxis, with dyspnea and cardiovascular collapse, in the operating theatre after receiving routine IV cefazolin prior to induction of anesthesia. She failed to improve with two doses of intramuscular epinephrine followed by two boluses of intravenous epinephrine, but responded to an epinephrine infusion. She was assessed by Internal Medicine and discharged home the following day. This event demonstrates the speed, severity, and profound hypotension in an allergic reaction from intravenous medication, challenges in managing anaphylaxis, and importance of prompt administration of epinephrine via IM route, followed by IV if necessary, in the OR. The case highlighted the inability to ascertain the causative agent through typical allergy testing.http://dx.doi.org/10.1155/2020/5283279 |
| spellingShingle | Sayed Hafizi Christine Nadeau Mohamed Gazarin Emily Mulligan Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit Case Reports in Surgery |
| title | Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit |
| title_full | Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit |
| title_fullStr | Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit |
| title_full_unstemmed | Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit |
| title_short | Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit |
| title_sort | refractory unforeseen anaphylaxis case in a rural or unit |
| url | http://dx.doi.org/10.1155/2020/5283279 |
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