Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus
In Russia, sulfonylurea drugs are extensively prescribed to patients with type 2 diabetes mellitus. This work was designed to study pharmacoeconomicaspects of application of 2nd generation sulfonylureas based on the results of the GUIDE study comparing effects of therapy with gliclazide modifiedrele...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2011-09-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/6234 |
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| author | Alla Vsevolodovna Rudakova |
| author_facet | Alla Vsevolodovna Rudakova |
| author_sort | Alla Vsevolodovna Rudakova |
| collection | DOAJ |
| description | In Russia, sulfonylurea drugs are extensively prescribed to patients with type 2 diabetes mellitus. This work was designed to study pharmacoeconomicaspects of application of 2nd generation sulfonylureas based on the results of the GUIDE study comparing effects of therapy with gliclazide modifiedrelease (diabeton MV) and glimepiride (amaryl). The two drugs are known to be equally effective, but gliclazide creates a much smaller risk ofhypoglycemia than glymepiride. Cost-effectiveness analysis showed that the use of gliclazide cuts the costs of therapy by 40%. It is concluded that thechoice of gliclazide modified release is economically more feasible than glimepiride. |
| format | Article |
| id | doaj-art-7fc1edfe2f104d5aae5849035a838ec8 |
| institution | Kabale University |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2011-09-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-7fc1edfe2f104d5aae5849035a838ec82025-08-20T03:47:54ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782011-09-0114311111210.14341/2072-0351-62346192Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitusAlla Vsevolodovna Rudakova0Sankt-Peterburg Chemicopharmaceutical Academy, Sankt-PeterburgIn Russia, sulfonylurea drugs are extensively prescribed to patients with type 2 diabetes mellitus. This work was designed to study pharmacoeconomicaspects of application of 2nd generation sulfonylureas based on the results of the GUIDE study comparing effects of therapy with gliclazide modifiedrelease (diabeton MV) and glimepiride (amaryl). The two drugs are known to be equally effective, but gliclazide creates a much smaller risk ofhypoglycemia than glymepiride. Cost-effectiveness analysis showed that the use of gliclazide cuts the costs of therapy by 40%. It is concluded that thechoice of gliclazide modified release is economically more feasible than glimepiride.https://www.dia-endojournals.ru/jour/article/view/6234type 2 diabetes mellitussulfonylureashypoglycemiacost-effectiveness analysis |
| spellingShingle | Alla Vsevolodovna Rudakova Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus Сахарный диабет type 2 diabetes mellitus sulfonylureas hypoglycemia cost-effectiveness analysis |
| title | Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| title_full | Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| title_fullStr | Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| title_full_unstemmed | Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| title_short | Pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| title_sort | pharmacoeconomic aspects of the use of sulfonylurea drugs in type 2 diabetes mellitus |
| topic | type 2 diabetes mellitus sulfonylureas hypoglycemia cost-effectiveness analysis |
| url | https://www.dia-endojournals.ru/jour/article/view/6234 |
| work_keys_str_mv | AT allavsevolodovnarudakova pharmacoeconomicaspectsoftheuseofsulfonylureadrugsintype2diabetesmellitus |