Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)

Abstract Research on how plants respond to hypoxia has concentrated on model organisms where tissues can only survive hypoxic conditions for a few hours to a few days. In contrast, hypoxic conditions are used commercially as a method to prolong the shelf life of Malus domestica (apple) fruit for up...

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Main Authors: John A. Hadish, Heidi L. Hargarten, Huiting Zhang, James P. Mattheis, Stephen P. Ficklin, Loren A. Honaas
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Plant Direct
Subjects:
Online Access:https://doi.org/10.1002/pld3.70025
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author John A. Hadish
Heidi L. Hargarten
Huiting Zhang
James P. Mattheis
Stephen P. Ficklin
Loren A. Honaas
author_facet John A. Hadish
Heidi L. Hargarten
Huiting Zhang
James P. Mattheis
Stephen P. Ficklin
Loren A. Honaas
author_sort John A. Hadish
collection DOAJ
description Abstract Research on how plants respond to hypoxia has concentrated on model organisms where tissues can only survive hypoxic conditions for a few hours to a few days. In contrast, hypoxic conditions are used commercially as a method to prolong the shelf life of Malus domestica (apple) fruit for up to a year of storage without substantial changes in fruit quality, not to mention a lack of tissue death. This ability of apples to withstand protracted hypoxic conditions is an interesting adaptation that has had limited molecular investigation despite its economic importance. Here, we investigate the long‐term apple hypoxia response using a time‐course RNA‐seq analysis of several postharvest storage conditions. We use phylogenetics, differential expression, and regulatory networks to identify genes that regulate and are regulated by the hypoxia response. We identify potential neofunctionalization of core‐hypoxia response genes in apples, including novel regulation of group VII ethylene response factor (ERF VII) and plant cysteine oxidase (PCO) family members.
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spelling doaj-art-7fba52c550e54f78bca2ad5cb20da5e32025-08-20T02:50:45ZengWileyPlant Direct2475-44552024-12-01812n/an/a10.1002/pld3.70025Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)John A. Hadish0Heidi L. Hargarten1Huiting Zhang2James P. Mattheis3Stephen P. Ficklin4Loren A. Honaas5Molecular Plant Science Program Washington State University Pullman WA USAUSDA Agricultural Research Service Physiology and Pathology of Tree Fruits Research Wenatchee WA USADepartment of Horticulture Washington State University Pullman WA USAUSDA Agricultural Research Service Physiology and Pathology of Tree Fruits Research Wenatchee WA USAMolecular Plant Science Program Washington State University Pullman WA USAUSDA Agricultural Research Service Physiology and Pathology of Tree Fruits Research Wenatchee WA USAAbstract Research on how plants respond to hypoxia has concentrated on model organisms where tissues can only survive hypoxic conditions for a few hours to a few days. In contrast, hypoxic conditions are used commercially as a method to prolong the shelf life of Malus domestica (apple) fruit for up to a year of storage without substantial changes in fruit quality, not to mention a lack of tissue death. This ability of apples to withstand protracted hypoxic conditions is an interesting adaptation that has had limited molecular investigation despite its economic importance. Here, we investigate the long‐term apple hypoxia response using a time‐course RNA‐seq analysis of several postharvest storage conditions. We use phylogenetics, differential expression, and regulatory networks to identify genes that regulate and are regulated by the hypoxia response. We identify potential neofunctionalization of core‐hypoxia response genes in apples, including novel regulation of group VII ethylene response factor (ERF VII) and plant cysteine oxidase (PCO) family members.https://doi.org/10.1002/pld3.70025hypoxiaM. domesticaphylogenomicspostharvesttranscription factors
spellingShingle John A. Hadish
Heidi L. Hargarten
Huiting Zhang
James P. Mattheis
Stephen P. Ficklin
Loren A. Honaas
Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
Plant Direct
hypoxia
M. domestica
phylogenomics
postharvest
transcription factors
title Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
title_full Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
title_fullStr Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
title_full_unstemmed Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
title_short Transcriptomics of long‐term, low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple (Malus domestica)
title_sort transcriptomics of long term low oxygen storage coupled with ethylene signaling interference suggests neofunctionalization of hypoxia response pathways in apple malus domestica
topic hypoxia
M. domestica
phylogenomics
postharvest
transcription factors
url https://doi.org/10.1002/pld3.70025
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