Clinical study of adebrelimab in combination with apatinib and irinotecan for PD-1 inhibitor-ineffective advanced-stage gastric cancer: study protocol for a single-arm, single-centre, exploratory trial

Introduction Immunotherapy has revolutionised cancer treatment. Immune checkpoint inhibitors have demonstrated significant efficacy across multiple tumour types, including gastric cancer, where several approved programmed cell death 1/programmed cell death-ligand 1 (PD-1/PD-L1) inhibitors show promi...

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Main Authors: Tao Liu, Long Bai, Jiayi Gu, Yujing Guan, Yeqian Zhang, Bo Ni, Hao-yu Zhang, Muerzhate Aimaiti, Shuchang Wang, Ben Yue, Xiang Xia, Zizhen Zhang
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e089286.full
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