Characterization of the Rbfox3‐IRES‐iCre knock‐in mouse: Revealing gene recombination activity in neural and non‐neural peripheral tissues

Characterization of the Rbfox3‐IRES‐iCre knock‐in mouse: Revealing gene recombination activity in neural and non‐neural peripheral tissues

Abstract In vivo cell type‐specific genetic recombination based on the Cre‐loxP system has contributed to the understanding of biological processes and diseases. Neuronal nuclei (NeuN)/RBFOX3 is a widely used mature neuron marker in developmental biology and neuroscience. Here, we generated Rbfox3‐i...

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Bibliographic Details
Main Authors: Shiho Nishino, Misuzu Hashimoto, Swapna Paramanya Biswas, Natsuki Mikami, Yoshikazu Hasegawa, Hayate Suzuki, Woojin Kang, Seiya Mizuno, Kazuya Murata
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:FASEB BioAdvances
Subjects:
bladder
Cre‐loxP
gene recombination
germline
heart
knock‐in mice
Online Access:https://doi.org/10.1096/fba.2024-00143
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