A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy.
<h4>Objectives</h4>To compare the perioperative and early renal functional outcomes of RPN with OPN for kidney tumors.<h4>Materials and methods</h4>A total of 209 RPN or OPN patients with availability of preoperative cross-sectional imaging since 2009 at our center were inclu...
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094195&type=printable |
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| author | Zhenjie Wu Mingmin Li Le Qu Huamao Ye Bing Liu Qing Yang Jing Sheng Liang Xiao Chen Lv Bo Yang Xu Gao Xiaofeng Gao Chuanliang Xu Jianguo Hou Yinghao Sun Linhui Wang |
| author_facet | Zhenjie Wu Mingmin Li Le Qu Huamao Ye Bing Liu Qing Yang Jing Sheng Liang Xiao Chen Lv Bo Yang Xu Gao Xiaofeng Gao Chuanliang Xu Jianguo Hou Yinghao Sun Linhui Wang |
| author_sort | Zhenjie Wu |
| collection | DOAJ |
| description | <h4>Objectives</h4>To compare the perioperative and early renal functional outcomes of RPN with OPN for kidney tumors.<h4>Materials and methods</h4>A total of 209 RPN or OPN patients with availability of preoperative cross-sectional imaging since 2009 at our center were included. To adjust for potential baseline confounders propensity-score matching was performed, which resulted in 94 OPNs matched to 51 RPNs. Perioperative and early renal functional outcomes were compared.<h4>Results</h4>In propensity-score matched analysis, RPN procedures were well tolerated and resulted in significant decreases in postoperative analgesic time (24 vs. 48 hr, p<0.001) and visual analog pain scale (3 vs. 4, p<0.001). Besides, the RPN patients had a significantly shorter LOS (9 vs. 11 days, p = 0.008) and less EBL (100 vs. 200 ml, p<0.001), but median operative time was significantly longer (229 vs. 182 min, p<0.001). Ischemia time, transfusion rates, complication rates, percentage eGFR decline and CKD upstaging were equivalent after RPN versus OPN. In multivariable logistic regression analysis, RPN patients were less likely to have a prolonged LOS (odds ratio [OR]: 0.409; p = 0.016), while more likely to experience a longer operative time (OR: 4.296; p = 0.001). However, the statistical significance for the protective effect of RPN versus OPN in EBL was not confirmed by examining the risk of EBL≥400 ml (OR: 0.488; p = 0.212).<h4>Conclusions</h4>When adjusted for potential selection biases, RPN offers comparable perioperative and early renal functional outcomes to those of OPN, with the added advantage of improved postoperative pain control and a shorter LOS. |
| format | Article |
| id | doaj-art-7fa5d1f3f7f04190ac1db68a87f25fb7 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-7fa5d1f3f7f04190ac1db68a87f25fb72025-08-20T03:00:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9419510.1371/journal.pone.0094195A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy.Zhenjie WuMingmin LiLe QuHuamao YeBing LiuQing YangJing ShengLiang XiaoChen LvBo YangXu GaoXiaofeng GaoChuanliang XuJianguo HouYinghao SunLinhui Wang<h4>Objectives</h4>To compare the perioperative and early renal functional outcomes of RPN with OPN for kidney tumors.<h4>Materials and methods</h4>A total of 209 RPN or OPN patients with availability of preoperative cross-sectional imaging since 2009 at our center were included. To adjust for potential baseline confounders propensity-score matching was performed, which resulted in 94 OPNs matched to 51 RPNs. Perioperative and early renal functional outcomes were compared.<h4>Results</h4>In propensity-score matched analysis, RPN procedures were well tolerated and resulted in significant decreases in postoperative analgesic time (24 vs. 48 hr, p<0.001) and visual analog pain scale (3 vs. 4, p<0.001). Besides, the RPN patients had a significantly shorter LOS (9 vs. 11 days, p = 0.008) and less EBL (100 vs. 200 ml, p<0.001), but median operative time was significantly longer (229 vs. 182 min, p<0.001). Ischemia time, transfusion rates, complication rates, percentage eGFR decline and CKD upstaging were equivalent after RPN versus OPN. In multivariable logistic regression analysis, RPN patients were less likely to have a prolonged LOS (odds ratio [OR]: 0.409; p = 0.016), while more likely to experience a longer operative time (OR: 4.296; p = 0.001). However, the statistical significance for the protective effect of RPN versus OPN in EBL was not confirmed by examining the risk of EBL≥400 ml (OR: 0.488; p = 0.212).<h4>Conclusions</h4>When adjusted for potential selection biases, RPN offers comparable perioperative and early renal functional outcomes to those of OPN, with the added advantage of improved postoperative pain control and a shorter LOS.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094195&type=printable |
| spellingShingle | Zhenjie Wu Mingmin Li Le Qu Huamao Ye Bing Liu Qing Yang Jing Sheng Liang Xiao Chen Lv Bo Yang Xu Gao Xiaofeng Gao Chuanliang Xu Jianguo Hou Yinghao Sun Linhui Wang A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. PLoS ONE |
| title | A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. |
| title_full | A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. |
| title_fullStr | A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. |
| title_full_unstemmed | A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. |
| title_short | A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy. |
| title_sort | propensity score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094195&type=printable |
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