Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia
Purpose: To describe a premature neonate with thrombocytopenia and retinal hemorrhage. Observation: A 33 week premature neonate with neonatal thrombocytopenia (34 × 109 platelet) was found to have left eye retinal hemorrhage. Bilateral retinal exam showed a healthy optic nerve and macula. A 10–12 di...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993625000635 |
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| author | Samara J. Hamou Iniya K. Adhan Maureen E. Lloyd Barry N. Wasserman |
| author_facet | Samara J. Hamou Iniya K. Adhan Maureen E. Lloyd Barry N. Wasserman |
| author_sort | Samara J. Hamou |
| collection | DOAJ |
| description | Purpose: To describe a premature neonate with thrombocytopenia and retinal hemorrhage. Observation: A 33 week premature neonate with neonatal thrombocytopenia (34 × 109 platelet) was found to have left eye retinal hemorrhage. Bilateral retinal exam showed a healthy optic nerve and macula. A 10–12 disc diameter large nasal subretinal hemorrhage with an intraretinal white-centered hemorrhage was found. No other retinal abnormalities were found. Resolution of the hemorrhage occurred over the next three months. By this time, thrombocytopenia resolved (final platelet count: 259 × 109/L), and the patient was able to fix and follow. Conclusions and importance: Neonatal thrombocytopenia associated retinal hemorrhage is not commonly reported in the literature. Further research will elucidate whether newborn retinal screening should be recommended for all neonates with thrombocytopenia. |
| format | Article |
| id | doaj-art-7fa4fd8adfd84a05b82b2f740392455a |
| institution | DOAJ |
| issn | 2451-9936 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj-art-7fa4fd8adfd84a05b82b2f740392455a2025-08-20T03:10:32ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362025-06-013810231010.1016/j.ajoc.2025.102310Retinal hemorrhage associated with neonatal idiopathic thrombocytopeniaSamara J. Hamou0Iniya K. Adhan1Maureen E. Lloyd2Barry N. Wasserman3Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA; Corresponding author. Dept. of Pediatric Ophthalmology and Strabismus, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut St. 12th Floor, Philadelphia, PA, 1910 7, USA.Department of Pediatric Ophthalmology, Wills Eye Hospital, Philadelphia, PA, USADepartment of Pediatric Ophthalmology, Wills Eye Hospital, Philadelphia, PA, USASidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA; Department of Pediatric Ophthalmology, Wills Eye Hospital, Philadelphia, PA, USAPurpose: To describe a premature neonate with thrombocytopenia and retinal hemorrhage. Observation: A 33 week premature neonate with neonatal thrombocytopenia (34 × 109 platelet) was found to have left eye retinal hemorrhage. Bilateral retinal exam showed a healthy optic nerve and macula. A 10–12 disc diameter large nasal subretinal hemorrhage with an intraretinal white-centered hemorrhage was found. No other retinal abnormalities were found. Resolution of the hemorrhage occurred over the next three months. By this time, thrombocytopenia resolved (final platelet count: 259 × 109/L), and the patient was able to fix and follow. Conclusions and importance: Neonatal thrombocytopenia associated retinal hemorrhage is not commonly reported in the literature. Further research will elucidate whether newborn retinal screening should be recommended for all neonates with thrombocytopenia.http://www.sciencedirect.com/science/article/pii/S2451993625000635Retinopathy of prematurityPediatricsNeonatal Idiopathic ThrombocytopeniaRetinal hemorrhage |
| spellingShingle | Samara J. Hamou Iniya K. Adhan Maureen E. Lloyd Barry N. Wasserman Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia American Journal of Ophthalmology Case Reports Retinopathy of prematurity Pediatrics Neonatal Idiopathic Thrombocytopenia Retinal hemorrhage |
| title | Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| title_full | Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| title_fullStr | Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| title_full_unstemmed | Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| title_short | Retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| title_sort | retinal hemorrhage associated with neonatal idiopathic thrombocytopenia |
| topic | Retinopathy of prematurity Pediatrics Neonatal Idiopathic Thrombocytopenia Retinal hemorrhage |
| url | http://www.sciencedirect.com/science/article/pii/S2451993625000635 |
| work_keys_str_mv | AT samarajhamou retinalhemorrhageassociatedwithneonatalidiopathicthrombocytopenia AT iniyakadhan retinalhemorrhageassociatedwithneonatalidiopathicthrombocytopenia AT maureenelloyd retinalhemorrhageassociatedwithneonatalidiopathicthrombocytopenia AT barrynwasserman retinalhemorrhageassociatedwithneonatalidiopathicthrombocytopenia |