Reduced glutathione ameliorates sepsis-induced acute kidney injury in mouse model: involvement of cuproptosis

Reduced glutathione ameliorates sepsis-induced acute kidney injury in mouse model: involvement of cuproptosis

Background Cuproptosis, a copper-induced form of programmed cell death, has been implicated in the pathogenesis of acute kidney injury (AKI) and sepsis. Reduced glutathione (GSH), a potent antioxidant, exhibits both anti-inflammatory and anti-oxidative properties. However, its potential role in modu...

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Bibliographic Details
Main Authors: Lu Wang, Long Jiang, Jingjing Wang, Wen Tang, Zhigao Wang, Rennan Guo, Daquan Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Reduced GSH
AKI
sepsis cuproptosis
CLP
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2518227
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