Automated detection and de novo structure modeling of nucleic acids from cryo-EM maps
Abstract Cryo-electron microscopy (cryo-EM) is one of the most powerful experimental methods for macromolecular structure determination. However, accurate DNA/RNA structure modeling from cryo-EM maps is still challenging especially for protein-DNA/RNA or multi-chain DNA/RNA complexes. Here we propos...
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| Main Authors: | Tao Li, Hong Cao, Jiahua He, Sheng-You Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53721-4 |
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