Automated detection and de novo structure modeling of nucleic acids from cryo-EM maps

Abstract Cryo-electron microscopy (cryo-EM) is one of the most powerful experimental methods for macromolecular structure determination. However, accurate DNA/RNA structure modeling from cryo-EM maps is still challenging especially for protein-DNA/RNA or multi-chain DNA/RNA complexes. Here we propos...

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Bibliographic Details
Main Authors: Tao Li, Hong Cao, Jiahua He, Sheng-You Huang
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53721-4
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