Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia
Background. Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite of worldwide distribution. There is limited information about the seroprevalence of toxoplasmosis in the southern area of Saudi Arabia. The current study was carried out to determine the prevalence of T. gondii...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/913950 |
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| author | Hussein Aqeely Eman K. El-Gayar Darakhshan Perveen Khan Abdullah Najmi Ayesha Alvi Ibrahim Bani Mohamed Salih Mahfouz Saif Elden Abdalla Ibrahim M. Elhassan |
| author_facet | Hussein Aqeely Eman K. El-Gayar Darakhshan Perveen Khan Abdullah Najmi Ayesha Alvi Ibrahim Bani Mohamed Salih Mahfouz Saif Elden Abdalla Ibrahim M. Elhassan |
| author_sort | Hussein Aqeely |
| collection | DOAJ |
| description | Background. Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite of worldwide distribution. There is limited information about the seroprevalence of toxoplasmosis in the southern area of Saudi Arabia. The current study was carried out to determine the prevalence of T. gondii in pregnant women in Jazan province. Materials and Methods. The study was conducted between January and June 2013 and included 195 pregnant women, data on sociodemographic and predisposing factors were collected from each participant. Venous blood samples were collected following standard operating procedures. Serological analysis for latent toxoplasmosis (levels of IgG) and active toxoplasmosis (IgM) was done using Enzyme Linked Immunosorbent Assay (ELISA). Results. The overall seroprevalence of T. gondii in the study area was 24.1%. The seroprevalence of anti-Toxoplasma IgG was 20% (39 out of 195), whereas IgM seropositivity was 6.2% (12 out of 195). Only 4 pregnant women tested positive for both IgG and IgM. The highest IgG and IgM seroprevalence was among the study participants aged 35 to 39 years (13.5% and 35.1%, resp.). The seropositivity rate of T. gondii-specific antibodies was higher among pregnant women from the urban areas than those from rural communities (7.4% versus 0% and 21% versus 15.4% for IgM and IgG, resp.). Conclusions. The seroprevalence of T. gondii was high in pregnant woman in Jazan. The prevalence of toxoplasmosis increases with increase of age. Awareness health education program in Jazan needs to be maintained and developed to targeted pregnant women. |
| format | Article |
| id | doaj-art-7f816eae0f0648129d9c0fa2f2b0dba1 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-7f816eae0f0648129d9c0fa2f2b0dba12025-02-03T01:12:50ZengWileyJournal of Tropical Medicine1687-96861687-96942014-01-01201410.1155/2014/913950913950Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi ArabiaHussein Aqeely0Eman K. El-Gayar1Darakhshan Perveen Khan2Abdullah Najmi3Ayesha Alvi4Ibrahim Bani5Mohamed Salih Mahfouz6Saif Elden Abdalla7Ibrahim M. Elhassan8College of Medicine, Jazan University, Saudi ArabiaCollege of Medicine, Jazan University, Saudi ArabiaCollege of Applied Medical Sciences, Jazan University, Saudi ArabiaCollege of Applied Medical Sciences, Jazan University, Saudi ArabiaDepartment of Obstetrics and Gynecology, Jazan General Hospital, Saudi ArabiaCollege of Medicine, Jazan University, Saudi ArabiaCollege of Medicine, Jazan University, Saudi ArabiaCenter of Biomedical Research, Jazan University, Saudi ArabiaDepartment of Microbiology, College of Medicine, Jazan University, Jazan, Saudi ArabiaBackground. Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite of worldwide distribution. There is limited information about the seroprevalence of toxoplasmosis in the southern area of Saudi Arabia. The current study was carried out to determine the prevalence of T. gondii in pregnant women in Jazan province. Materials and Methods. The study was conducted between January and June 2013 and included 195 pregnant women, data on sociodemographic and predisposing factors were collected from each participant. Venous blood samples were collected following standard operating procedures. Serological analysis for latent toxoplasmosis (levels of IgG) and active toxoplasmosis (IgM) was done using Enzyme Linked Immunosorbent Assay (ELISA). Results. The overall seroprevalence of T. gondii in the study area was 24.1%. The seroprevalence of anti-Toxoplasma IgG was 20% (39 out of 195), whereas IgM seropositivity was 6.2% (12 out of 195). Only 4 pregnant women tested positive for both IgG and IgM. The highest IgG and IgM seroprevalence was among the study participants aged 35 to 39 years (13.5% and 35.1%, resp.). The seropositivity rate of T. gondii-specific antibodies was higher among pregnant women from the urban areas than those from rural communities (7.4% versus 0% and 21% versus 15.4% for IgM and IgG, resp.). Conclusions. The seroprevalence of T. gondii was high in pregnant woman in Jazan. The prevalence of toxoplasmosis increases with increase of age. Awareness health education program in Jazan needs to be maintained and developed to targeted pregnant women.http://dx.doi.org/10.1155/2014/913950 |
| spellingShingle | Hussein Aqeely Eman K. El-Gayar Darakhshan Perveen Khan Abdullah Najmi Ayesha Alvi Ibrahim Bani Mohamed Salih Mahfouz Saif Elden Abdalla Ibrahim M. Elhassan Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia Journal of Tropical Medicine |
| title | Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia |
| title_full | Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia |
| title_fullStr | Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia |
| title_full_unstemmed | Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia |
| title_short | Seroepidemiology of Toxoplasma gondii amongst Pregnant Women in Jazan Province, Saudi Arabia |
| title_sort | seroepidemiology of toxoplasma gondii amongst pregnant women in jazan province saudi arabia |
| url | http://dx.doi.org/10.1155/2014/913950 |
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