FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

The article summarizes the results of studies on the composition of microbial communities in stool samples of patients with chronic obstructive pulmonary disease (COPD) compared with healthy volunteers using genome-metagenomic sequencing. It is shown that the microbial community of the intestine in...

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Main Authors: L. M. Ogorodova, V. M. Govorun, S. V. Fedosenko, M. A. Karnaushkina, I. V. Saltykova, D. G. Alekseyev, Ye. S. Kostrytikova, A. V. Tyakht, A. S. Popenko
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2014-10-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/221
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author L. M. Ogorodova
V. M. Govorun
S. V. Fedosenko
M. A. Karnaushkina
I. V. Saltykova
D. G. Alekseyev
Ye. S. Kostrytikova
A. V. Tyakht
A. S. Popenko
author_facet L. M. Ogorodova
V. M. Govorun
S. V. Fedosenko
M. A. Karnaushkina
I. V. Saltykova
D. G. Alekseyev
Ye. S. Kostrytikova
A. V. Tyakht
A. S. Popenko
author_sort L. M. Ogorodova
collection DOAJ
description The article summarizes the results of studies on the composition of microbial communities in stool samples of patients with chronic obstructive pulmonary disease (COPD) compared with healthy volunteers using genome-metagenomic sequencing. It is shown that the microbial community of the intestine in COPD patients is characterized as diverse taxonomic composition of metagenomes that the healthy volunteers microbiota. In this case, the normal composition of intestinal microbiota in patients with COPD is exposed to the qualitative and quantitative modifications. In contrast to healthy volunteers, the intestinal microbiota in patients with COPD is characterized by the presence of representatives of the Proteobacteria, as Citrobacter, Enterobacter, Eggerthella,Proteus, Salmonella, Anaerococcus, Clostridium difficile, Pseudomonas, as well as higher insemination fungus genusCandida (Candida dubliniensis and Candida albicans).
format Article
id doaj-art-7f7c5034eaa34338bb9ac4a1cea26415
institution Kabale University
issn 1682-0363
1819-3684
language English
publishDate 2014-10-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-7f7c5034eaa34338bb9ac4a1cea264152025-08-20T03:38:08ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-10-01135556110.20538/1682-0363-2014-5-55-61219FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASEL. M. Ogorodova0V. M. Govorun1S. V. Fedosenko2M. A. Karnaushkina3I. V. Saltykova4D. G. Alekseyev5Ye. S. Kostrytikova6A. V. Tyakht7A. S. Popenko8Siberian State Medical University, TomskResearch Institute for Physico-Chemical Medicine, FMBA, MoscowSiberian State Medical University, TomskA .I. Yevdokimov Moscow State University o f Medicine and Dentistry, MoscowSiberian State Medical University, TomskResearch Institute for Physico-Chemical Medicine, FMBA, MoscowResearch Institute for Physico-Chemical Medicine, FMBA, MoscowResearch Institute for Physico-Chemical Medicine, FMBA, MoscowResearch Institute for Physico-Chemical Medicine, FMBA, MoscowThe article summarizes the results of studies on the composition of microbial communities in stool samples of patients with chronic obstructive pulmonary disease (COPD) compared with healthy volunteers using genome-metagenomic sequencing. It is shown that the microbial community of the intestine in COPD patients is characterized as diverse taxonomic composition of metagenomes that the healthy volunteers microbiota. In this case, the normal composition of intestinal microbiota in patients with COPD is exposed to the qualitative and quantitative modifications. In contrast to healthy volunteers, the intestinal microbiota in patients with COPD is characterized by the presence of representatives of the Proteobacteria, as Citrobacter, Enterobacter, Eggerthella,Proteus, Salmonella, Anaerococcus, Clostridium difficile, Pseudomonas, as well as higher insemination fungus genusCandida (Candida dubliniensis and Candida albicans).https://bulletin.ssmu.ru/jour/article/view/221community of microorganisms of the intestinethe intestinal microbiotagenome-metagenomic sequencingcopd
spellingShingle L. M. Ogorodova
V. M. Govorun
S. V. Fedosenko
M. A. Karnaushkina
I. V. Saltykova
D. G. Alekseyev
Ye. S. Kostrytikova
A. V. Tyakht
A. S. Popenko
FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Бюллетень сибирской медицины
community of microorganisms of the intestine
the intestinal microbiota
genome-metagenomic sequencing
copd
title FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
title_full FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
title_fullStr FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
title_full_unstemmed FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
title_short FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
title_sort features of the intestinal microbiota in patients with chronic obstructive pulmonary disease
topic community of microorganisms of the intestine
the intestinal microbiota
genome-metagenomic sequencing
copd
url https://bulletin.ssmu.ru/jour/article/view/221
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