Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature
The introduction of screening mammograms has revolutionized the early detection of breast cancer. However, it remains the most common cancer in women in the United States, excluding skin cancer. As the incidence rates continue to rise, unusual presentations have become more frequent. Additionally, h...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-04-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096251334232 |
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| author | Jayalekshmi Jayakumar MD Manasa Ginjupalli MD Giovannie Isaac Coss MD Fiqe Khan MD Daniel Stein MD Davin Turku MD Khalimullah Quadri MD |
| author_facet | Jayalekshmi Jayakumar MD Manasa Ginjupalli MD Giovannie Isaac Coss MD Fiqe Khan MD Daniel Stein MD Davin Turku MD Khalimullah Quadri MD |
| author_sort | Jayalekshmi Jayakumar MD |
| collection | DOAJ |
| description | The introduction of screening mammograms has revolutionized the early detection of breast cancer. However, it remains the most common cancer in women in the United States, excluding skin cancer. As the incidence rates continue to rise, unusual presentations have become more frequent. Additionally, healthcare barriers can lead to delayed detection of breast cancer, resulting in unexpected complications. The occurrence of pyogenic liver abscess (PLA) in diabetic cancer patients, due to the synergistic effect of insulin-like growth factor-1 in tumorigenesis and abscess formation, is well documented. PLA is also prevalent in hepatocellular, colorectal, and pancreato-biliary tumors. However, the occurrence of PLA as an initial presentation of isolated advanced breast cancer without these comorbidities is understudied. This may be due to direct spread of infection from affected skin or spread via lymphatics or vasculature in the setting of immunosuppression from cancer. We present an exceedingly rare case of PLA, complicated by pulmonary embolism, in an elderly female with newly diagnosed stage IIIB breast carcinoma. |
| format | Article |
| id | doaj-art-7f7b5810a9e24e8bb81a2137ad8729b9 |
| institution | Kabale University |
| issn | 2324-7096 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj-art-7f7b5810a9e24e8bb81a2137ad8729b92025-08-20T03:53:33ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962025-04-011310.1177/23247096251334232Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of LiteratureJayalekshmi Jayakumar MD0Manasa Ginjupalli MD1Giovannie Isaac Coss MD2Fiqe Khan MD3Daniel Stein MD4Davin Turku MD5Khalimullah Quadri MD6The Brooklyn Hospital Centre, New York, USAThe Brooklyn Hospital Centre, New York, USARush University Medical Centre, Chicago, IL, USAThe Brooklyn Hospital Centre, New York, USAThe Brooklyn Hospital Centre, New York, USAThe Brooklyn Hospital Centre, New York, USAThe Brooklyn Hospital Centre, New York, USAThe introduction of screening mammograms has revolutionized the early detection of breast cancer. However, it remains the most common cancer in women in the United States, excluding skin cancer. As the incidence rates continue to rise, unusual presentations have become more frequent. Additionally, healthcare barriers can lead to delayed detection of breast cancer, resulting in unexpected complications. The occurrence of pyogenic liver abscess (PLA) in diabetic cancer patients, due to the synergistic effect of insulin-like growth factor-1 in tumorigenesis and abscess formation, is well documented. PLA is also prevalent in hepatocellular, colorectal, and pancreato-biliary tumors. However, the occurrence of PLA as an initial presentation of isolated advanced breast cancer without these comorbidities is understudied. This may be due to direct spread of infection from affected skin or spread via lymphatics or vasculature in the setting of immunosuppression from cancer. We present an exceedingly rare case of PLA, complicated by pulmonary embolism, in an elderly female with newly diagnosed stage IIIB breast carcinoma.https://doi.org/10.1177/23247096251334232 |
| spellingShingle | Jayalekshmi Jayakumar MD Manasa Ginjupalli MD Giovannie Isaac Coss MD Fiqe Khan MD Daniel Stein MD Davin Turku MD Khalimullah Quadri MD Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature Journal of Investigative Medicine High Impact Case Reports |
| title | Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature |
| title_full | Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature |
| title_fullStr | Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature |
| title_full_unstemmed | Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature |
| title_short | Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature |
| title_sort | unveiling the link between breast cancer and liver abscess a case report and review of literature |
| url | https://doi.org/10.1177/23247096251334232 |
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