Characterization of a novel mouse model of multiple myeloma and its use in preclinical therapeutic assessment.
To aid preclinical development of novel therapeutics for myeloma, an in vivo model which recapitulates the human condition is required. An important feature of such a model is the interaction of myeloma cells with the bone marrow microenvironment, as this interaction modulates tumour activity and pr...
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| Main Authors: | Rosemary A Fryer, Timothy J Graham, Emma M Smith, Simon Walker-Samuel, Gareth J Morgan, Simon P Robinson, Faith E Davies |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0057641&type=printable |
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