Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies
Introduction: Exogenous and endogenous sex hormones, especially Progesterone agonists, may be causally linked to meningioma progression. Cessation of treatment leads to stabilization or regression of Progestin-induced meningioma. In many cases, avoiding sex hormone therapy may be possible in the con...
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Elsevier
2025-01-01
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| Series: | Brain and Spine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529424014103 |
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| author | Gilles Reuter Iulia Potorac Carlien de Herdt Linda Ameryckx Géraldine Brichant Sébastien Froelich Bertrand Baussart Steven De Vleeschouwer Tomas Menovsky Tony Van Havenberghe Patrice Finet Michael Bruneau Axelle Pintiaux |
| author_facet | Gilles Reuter Iulia Potorac Carlien de Herdt Linda Ameryckx Géraldine Brichant Sébastien Froelich Bertrand Baussart Steven De Vleeschouwer Tomas Menovsky Tony Van Havenberghe Patrice Finet Michael Bruneau Axelle Pintiaux |
| author_sort | Gilles Reuter |
| collection | DOAJ |
| description | Introduction: Exogenous and endogenous sex hormones, especially Progesterone agonists, may be causally linked to meningioma progression. Cessation of treatment leads to stabilization or regression of Progestin-induced meningioma. In many cases, avoiding sex hormone therapy may be possible in the context of meningioma treatment. However, hormonal treatment is not always easily replaceable and concise real-world recommendations regarding sex hormones and meningioma are lacking. Material and methods: A combined effort was initiated between Neurosurgical, Gynaecological and Endocrinological societies of Belgium to gather relevant information regarding sex hormone therapies and meningioma. After complete literature review, consensual recommendations were established. Results: Collegial recommendations regarding sex hormones therapies and meningioma in the context of oral contraceptives, menopause hormonal treatment, fertility treatment, pregnancy and gender-affirming therapies are emitted and nuanced. Discussion and conclusion: Withdrawal and monitoring of sex hormone therapies are discussed in detail.A decision tree regarding Meningioma and Combined contraception, Progestin Contraception, Menopause Hormonal treatment, Progestin and Gender-affirming therapy is suggested. |
| format | Article |
| id | doaj-art-7f7514be26bc403f9d6bafb47344fa65 |
| institution | DOAJ |
| issn | 2772-5294 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain and Spine |
| spelling | doaj-art-7f7514be26bc403f9d6bafb47344fa652025-08-20T02:52:30ZengElsevierBrain and Spine2772-52942025-01-01510415410.1016/j.bas.2024.104154Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societiesGilles Reuter0Iulia Potorac1Carlien de Herdt2Linda Ameryckx3Géraldine Brichant4Sébastien Froelich5Bertrand Baussart6Steven De Vleeschouwer7Tomas Menovsky8Tony Van Havenberghe9Patrice Finet10Michael Bruneau11Axelle Pintiaux12Corresponding author.; Department of Neurosurgery, CHU de Liege, Liège, BelgiumDepartment of Endocrinology, CHU de Liege, Liège, BelgiumDepartment of Endocrinology, UZ Antwerpen, Antwerpen, BelgiumDepartment of Gynecology, UZ Antwerpen, Antwerpen, BelgiumDepartment of Gynecology, CHU de Liege, Liège, BelgiumDepartment of Neurosurgery, Hopital Lariboisiere, Paris, FranceDepartment of Neurosurgery, Hopital Lariboisiere, Paris, FranceDepartment of Neurosurgery, UZ Leuven, Leuven, BelgiumDepartment of Neurosurgery, UZ Antwerpen, Antwerpen, BelgiumDepartment of Neurosurgery, ZAS, Antwerpen, BelgiumDepartment of Neurosurgery, UCL Saint Luc, Brussels, BelgiumDepartment of Neurosurgery, UZ Brussels, Brussels, BelgiumDepartment of Gynecology, CHU de Liege, Liège, BelgiumIntroduction: Exogenous and endogenous sex hormones, especially Progesterone agonists, may be causally linked to meningioma progression. Cessation of treatment leads to stabilization or regression of Progestin-induced meningioma. In many cases, avoiding sex hormone therapy may be possible in the context of meningioma treatment. However, hormonal treatment is not always easily replaceable and concise real-world recommendations regarding sex hormones and meningioma are lacking. Material and methods: A combined effort was initiated between Neurosurgical, Gynaecological and Endocrinological societies of Belgium to gather relevant information regarding sex hormone therapies and meningioma. After complete literature review, consensual recommendations were established. Results: Collegial recommendations regarding sex hormones therapies and meningioma in the context of oral contraceptives, menopause hormonal treatment, fertility treatment, pregnancy and gender-affirming therapies are emitted and nuanced. Discussion and conclusion: Withdrawal and monitoring of sex hormone therapies are discussed in detail.A decision tree regarding Meningioma and Combined contraception, Progestin Contraception, Menopause Hormonal treatment, Progestin and Gender-affirming therapy is suggested.http://www.sciencedirect.com/science/article/pii/S2772529424014103MeningiomaProgestinOral contraceptiveMenopauseSex hormone therapy |
| spellingShingle | Gilles Reuter Iulia Potorac Carlien de Herdt Linda Ameryckx Géraldine Brichant Sébastien Froelich Bertrand Baussart Steven De Vleeschouwer Tomas Menovsky Tony Van Havenberghe Patrice Finet Michael Bruneau Axelle Pintiaux Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies Brain and Spine Meningioma Progestin Oral contraceptive Menopause Sex hormone therapy |
| title | Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies |
| title_full | Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies |
| title_fullStr | Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies |
| title_full_unstemmed | Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies |
| title_short | Recommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies |
| title_sort | recommendations on the management of meningioma and sex hormone therapy the results of a collaborative effort between neurosurgical endocrine and gynecological societies |
| topic | Meningioma Progestin Oral contraceptive Menopause Sex hormone therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2772529424014103 |
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