PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it

PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it

Gastric cancer (GC) is a common malignant tumor with high mortality, recurrence, and metastasis rates. Compound Kushen injection (CKI) combination chemotherapy has been clinically used for the treatment of GC in China for many years, but its underlying mechanisms of action remain unclear. Recent rep...

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Bibliographic Details
Main Authors: Chao Wu, Yifei Gao, Zhengsen Jin, Zhihong Huang, Haojia Wang, Shan Lu, Siyu Guo, Fanqin Zhang, Jingyuan Zhang, Jiaqi Huang, Xiaoyu Tao, Xinkui Liu, Xiaomeng Zhang, Leiming You, Qinglin Li, Jiarui Wu
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Pharmacological Research
Subjects:
PTPRG-AS1
Hsa-miR-421
KITLG
Gastric cancer
Compound Kushen injection
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825001689
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