Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.

<h4>Background</h4>Large households/families may create more happiness and offer more comprehensive healthcare among the members. We correlated household size to dementia mortality rate at population level for analysing its protecting role against dementia mortality.<h4>Methods<...

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Main Authors: Wenpeng You, Maciej Henneberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263309&type=printable
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author Wenpeng You
Maciej Henneberg
author_facet Wenpeng You
Maciej Henneberg
author_sort Wenpeng You
collection DOAJ
description <h4>Background</h4>Large households/families may create more happiness and offer more comprehensive healthcare among the members. We correlated household size to dementia mortality rate at population level for analysing its protecting role against dementia mortality.<h4>Methods</h4>This is a retrospective cross-sectional study. Dementia specific mortality rates of the 183 member states of World Health Organization were calculated and matched with the respective country data on household size, Gross Domestic Product (GDP), urban population and ageing. Scatter plots were produced to explore and visualize the correlations between household size and dementia mortality rates. Pearson's and nonparametric correlations were used to evaluate the strength and direction of the associations between household size and all other variables. Partial correlation of Pearson's approach was used to identify that household size protects against dementia regardless of the competing effects from ageing, GDP and urbanization. Multiple regression was used to identify significant predictors of dementia mortality.<h4>Results</h4>Household size was in a negative and moderately strong correlation (r = -0.6034, p < 0.001) with dementia mortality. This relationship was confirmed in both Pearson r (r = - 0.524, p<0.001) and nonparametric (rho  =  -0.579, p < 0.001) analyses. When we controlled for the contribution of ageing, socio-economic status and urban lifestyle in partial correlation analysis, large household was still in inverse and significant correlation to dementia mortality (r = -0.331, p <0.001). This suggested that, statistically, large household protect against dementia mortality regardless of the contributing effects of ageing, socio-economic status and urban lifestyle. Stepwise multiple regression analysis selected large household as the variable having the greatest contribution to dementia mortality with R2 = 0.263 while ageing was placed second increasing R2 to 0.259. GDP and urbanization were removed as having no statistically significant influence on dementia mortality.<h4>Conclusions</h4>While acknowledging ageing, urban lifestyle and greater GDP associated with dementia mortality, this study suggested that, at population level, household size was another risk factor for dementia mortality. As part of dementia prevention, healthcare practitioners should encourage people to increase their positive interactions with persons from their neighbourhood or other fields where large household/family size is hard to achieve.
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spelling doaj-art-7f6cb4f97ec84a28af3769430a1a2e422025-08-20T02:02:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01173e026330910.1371/journal.pone.0263309Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.Wenpeng YouMaciej Henneberg<h4>Background</h4>Large households/families may create more happiness and offer more comprehensive healthcare among the members. We correlated household size to dementia mortality rate at population level for analysing its protecting role against dementia mortality.<h4>Methods</h4>This is a retrospective cross-sectional study. Dementia specific mortality rates of the 183 member states of World Health Organization were calculated and matched with the respective country data on household size, Gross Domestic Product (GDP), urban population and ageing. Scatter plots were produced to explore and visualize the correlations between household size and dementia mortality rates. Pearson's and nonparametric correlations were used to evaluate the strength and direction of the associations between household size and all other variables. Partial correlation of Pearson's approach was used to identify that household size protects against dementia regardless of the competing effects from ageing, GDP and urbanization. Multiple regression was used to identify significant predictors of dementia mortality.<h4>Results</h4>Household size was in a negative and moderately strong correlation (r = -0.6034, p < 0.001) with dementia mortality. This relationship was confirmed in both Pearson r (r = - 0.524, p<0.001) and nonparametric (rho  =  -0.579, p < 0.001) analyses. When we controlled for the contribution of ageing, socio-economic status and urban lifestyle in partial correlation analysis, large household was still in inverse and significant correlation to dementia mortality (r = -0.331, p <0.001). This suggested that, statistically, large household protect against dementia mortality regardless of the contributing effects of ageing, socio-economic status and urban lifestyle. Stepwise multiple regression analysis selected large household as the variable having the greatest contribution to dementia mortality with R2 = 0.263 while ageing was placed second increasing R2 to 0.259. GDP and urbanization were removed as having no statistically significant influence on dementia mortality.<h4>Conclusions</h4>While acknowledging ageing, urban lifestyle and greater GDP associated with dementia mortality, this study suggested that, at population level, household size was another risk factor for dementia mortality. As part of dementia prevention, healthcare practitioners should encourage people to increase their positive interactions with persons from their neighbourhood or other fields where large household/family size is hard to achieve.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263309&type=printable
spellingShingle Wenpeng You
Maciej Henneberg
Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
PLoS ONE
title Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
title_full Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
title_fullStr Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
title_full_unstemmed Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
title_short Large household reduces dementia mortality: A cross-sectional data analysis of 183 populations.
title_sort large household reduces dementia mortality a cross sectional data analysis of 183 populations
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263309&type=printable
work_keys_str_mv AT wenpengyou largehouseholdreducesdementiamortalityacrosssectionaldataanalysisof183populations
AT maciejhenneberg largehouseholdreducesdementiamortalityacrosssectionaldataanalysisof183populations