Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil

Non-diphtheriae Corynebacterium species are usually considered as contaminants of clinical specimens due to their widely environmental distribution and colonization of the human skin and mucous membranes. However, these bacteria have been increasingly recognized as agents of life-threatening infect...

Full description

Saved in:
Bibliographic Details
Main Authors: Jaqueline Abel da Rocha, Natalia Chilinque Zambão da Silva, Ana SDN Silva, Rafael Guaresma Garrido, Beatriz Meurer Moreira, Ianick Souto Martins
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2018-09-01
Series:Journal of Infection in Developing Countries
Subjects:
Online Access:https://jidc.org/index.php/journal/article/view/10587
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850193604293689344
author Jaqueline Abel da Rocha
Natalia Chilinque Zambão da Silva
Ana SDN Silva
Rafael Guaresma Garrido
Beatriz Meurer Moreira
Ianick Souto Martins
author_facet Jaqueline Abel da Rocha
Natalia Chilinque Zambão da Silva
Ana SDN Silva
Rafael Guaresma Garrido
Beatriz Meurer Moreira
Ianick Souto Martins
author_sort Jaqueline Abel da Rocha
collection DOAJ
description Non-diphtheriae Corynebacterium species are usually considered as contaminants of clinical specimens due to their widely environmental distribution and colonization of the human skin and mucous membranes. However, these bacteria have been increasingly recognized as agents of life-threatening infections mainly in individuals in immunosuppressive conditions. These organisms have vast variation in morphology and biochemical reaction, characteristics that make the correct identification of Corynebacterium at the species level extremely difficult using conventional phenotypic methods. The precise identification of C. amycolatum requires approaches rarely available in conventional clinical microbiology laboratories, such as API Coryne system, 16s rRNA and rpoB gene sequencing. In this setting, MALDI-TOF, a quick, accurate, and relatively unexpansive molecular technique, arises as a cost-effective alternative for characterizing these agents. Here, a rare and lethal case of endocarditis caused by C. amycolatum is presented. This is the first case of infective endocarditis due to C. amycolatum reported in Brazil.
format Article
id doaj-art-7f6aa149f2f045cfa9e619ef85fa098b
institution OA Journals
issn 1972-2680
language English
publishDate 2018-09-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-7f6aa149f2f045cfa9e619ef85fa098b2025-08-20T02:14:12ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802018-09-01120910.3855/jidc.10587Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in BrazilJaqueline Abel da Rocha0Natalia Chilinque Zambão da Silva1Ana SDN Silva2Rafael Guaresma Garrido3Beatriz Meurer Moreira4Ianick Souto Martins5Universidade Federal Fluminense, Niterói, RJ, BrazilUniversidade Federal Fluminense, Niterói, RJ, BrazilUniversidade Federal Fluminense, Niterói, RJ, BrazilInstituto Nacional de Cardiologia, Rio de Janeiro, BrazilUniversidade Federal do Rio de Janeiro, Rio de Janeiro, BrazilUniversidade Federal Fluminense, Niterói, RJ, Brazil Non-diphtheriae Corynebacterium species are usually considered as contaminants of clinical specimens due to their widely environmental distribution and colonization of the human skin and mucous membranes. However, these bacteria have been increasingly recognized as agents of life-threatening infections mainly in individuals in immunosuppressive conditions. These organisms have vast variation in morphology and biochemical reaction, characteristics that make the correct identification of Corynebacterium at the species level extremely difficult using conventional phenotypic methods. The precise identification of C. amycolatum requires approaches rarely available in conventional clinical microbiology laboratories, such as API Coryne system, 16s rRNA and rpoB gene sequencing. In this setting, MALDI-TOF, a quick, accurate, and relatively unexpansive molecular technique, arises as a cost-effective alternative for characterizing these agents. Here, a rare and lethal case of endocarditis caused by C. amycolatum is presented. This is the first case of infective endocarditis due to C. amycolatum reported in Brazil. https://jidc.org/index.php/journal/article/view/10587Early prosthetic valve endocarditisCorynebacterium amycolatumMALDI-TOF
spellingShingle Jaqueline Abel da Rocha
Natalia Chilinque Zambão da Silva
Ana SDN Silva
Rafael Guaresma Garrido
Beatriz Meurer Moreira
Ianick Souto Martins
Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
Journal of Infection in Developing Countries
Early prosthetic valve endocarditis
Corynebacterium amycolatum
MALDI-TOF
title Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
title_full Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
title_fullStr Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
title_full_unstemmed Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
title_short Early prosthetic valve endocarditis caused by Corynebacterium amycolatum: the first case reported in Brazil
title_sort early prosthetic valve endocarditis caused by corynebacterium amycolatum the first case reported in brazil
topic Early prosthetic valve endocarditis
Corynebacterium amycolatum
MALDI-TOF
url https://jidc.org/index.php/journal/article/view/10587
work_keys_str_mv AT jaquelineabeldarocha earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil
AT nataliachilinquezambaodasilva earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil
AT anasdnsilva earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil
AT rafaelguaresmagarrido earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil
AT beatrizmeurermoreira earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil
AT ianicksoutomartins earlyprostheticvalveendocarditiscausedbycorynebacteriumamycolatumthefirstcasereportedinbrazil