Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance
At present, there are no bioresorbable systems available for the treatment of aortic coarctation in pediatric patients. However, experience with off-label used systems and knowledge of bioresorbable scaffolds in other applications suggest potential benefits. While stenting techniques are typically p...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2024-12-01
|
| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2024-2058 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850055317523529728 |
|---|---|
| author | Fiedler Nicklas Oschatz Stefan Ince Hüseyin Grabow Niels Lebahn Kerstin |
| author_facet | Fiedler Nicklas Oschatz Stefan Ince Hüseyin Grabow Niels Lebahn Kerstin |
| author_sort | Fiedler Nicklas |
| collection | DOAJ |
| description | At present, there are no bioresorbable systems available for the treatment of aortic coarctation in pediatric patients. However, experience with off-label used systems and knowledge of bioresorbable scaffolds in other applications suggest potential benefits. While stenting techniques are typically preferred for older children, there have been encouraging reports regarding their use in newborns and very young infants recently. Bioresorbable scaffolds could potentially close the technological gap in this area and serve as a bridge therapy for non-operable patients. This work identifies geometric and loading aspects in the light of current literature to improve the growth-responsive development of new scaffolds for the treatment of congenital heart diseases with pediatric-specific characteristics. |
| format | Article |
| id | doaj-art-7f66840fcd6f49a2b5229b08b206952f |
| institution | DOAJ |
| issn | 2364-5504 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj-art-7f66840fcd6f49a2b5229b08b206952f2025-08-20T02:51:59ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110424024310.1515/cdbme-2024-2058Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical PerformanceFiedler Nicklas0Oschatz Stefan1Ince Hüseyin2Grabow Niels3Lebahn Kerstin4Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich- Barnewitz-Str. 4, 18119Rostock, GermanyInstitute for Biomedical Engineering, Rostock University Medical Center,Rostock, GermanyDepartment of Cardiology, Rostock University Medical Center,Rostock, GermanyInstitute for Biomedical Engineering, Rostock University Medical Center,Rostock, GermanyInstitute for Biomedical Engineering, Rostock University Medical Center,Rostock, GermanyAt present, there are no bioresorbable systems available for the treatment of aortic coarctation in pediatric patients. However, experience with off-label used systems and knowledge of bioresorbable scaffolds in other applications suggest potential benefits. While stenting techniques are typically preferred for older children, there have been encouraging reports regarding their use in newborns and very young infants recently. Bioresorbable scaffolds could potentially close the technological gap in this area and serve as a bridge therapy for non-operable patients. This work identifies geometric and loading aspects in the light of current literature to improve the growth-responsive development of new scaffolds for the treatment of congenital heart diseases with pediatric-specific characteristics.https://doi.org/10.1515/cdbme-2024-2058bioresobable scaffoldaortic coarctationcongenital heart diseasepediatric cardiology |
| spellingShingle | Fiedler Nicklas Oschatz Stefan Ince Hüseyin Grabow Niels Lebahn Kerstin Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance Current Directions in Biomedical Engineering bioresobable scaffold aortic coarctation congenital heart disease pediatric cardiology |
| title | Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance |
| title_full | Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance |
| title_fullStr | Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance |
| title_full_unstemmed | Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance |
| title_short | Bioresorbable Vascular Scaffolds for the Treatment of Aortic Coarctation in Pediatric Patients – Aspects of Dimensional and Mechanical Performance |
| title_sort | bioresorbable vascular scaffolds for the treatment of aortic coarctation in pediatric patients aspects of dimensional and mechanical performance |
| topic | bioresobable scaffold aortic coarctation congenital heart disease pediatric cardiology |
| url | https://doi.org/10.1515/cdbme-2024-2058 |
| work_keys_str_mv | AT fiedlernicklas bioresorbablevascularscaffoldsforthetreatmentofaorticcoarctationinpediatricpatientsaspectsofdimensionalandmechanicalperformance AT oschatzstefan bioresorbablevascularscaffoldsforthetreatmentofaorticcoarctationinpediatricpatientsaspectsofdimensionalandmechanicalperformance AT incehuseyin bioresorbablevascularscaffoldsforthetreatmentofaorticcoarctationinpediatricpatientsaspectsofdimensionalandmechanicalperformance AT grabowniels bioresorbablevascularscaffoldsforthetreatmentofaorticcoarctationinpediatricpatientsaspectsofdimensionalandmechanicalperformance AT lebahnkerstin bioresorbablevascularscaffoldsforthetreatmentofaorticcoarctationinpediatricpatientsaspectsofdimensionalandmechanicalperformance |