Neuropathological findings in essential tremor
Essential tremor (ET) is one of the most common neurological conditions and the most common movement disorder. The pathophysiological mechanisms that underlie this entity have not yet been described. However, recent post-mortem brain studies have provided useful insight into the underlying pathology...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-06-01
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| Series: | Folia Neuropathologica |
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| Online Access: | https://www.termedia.pl/Neuropathological-findings-in-essential-tremor,20,54271,1,1.html |
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| author | Ioannis Mavroudis Foivos Petridis |
| author_facet | Ioannis Mavroudis Foivos Petridis |
| author_sort | Ioannis Mavroudis |
| collection | DOAJ |
| description | Essential tremor (ET) is one of the most common neurological conditions and the most common movement disorder. The pathophysiological mechanisms that underlie this entity have not yet been described. However, recent post-mortem brain studies have provided useful insight into the underlying pathology of ET. Two brain areas have been consistently found to present neuropathological alterations in patients with ET: the brainstem, for presence of Lewy bodies or neuronal depletion, and the cerebellum, regarding Purkinje cells’ morphology and density. In the present study we aim to review the literature on the main neuropathological findings in ET brains. |
| format | Article |
| id | doaj-art-7f62f69990ff4b4fb2d294a2885d8ab0 |
| institution | OA Journals |
| issn | 1641-4640 1509-572X |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Folia Neuropathologica |
| spelling | doaj-art-7f62f69990ff4b4fb2d294a2885d8ab02025-08-20T01:50:39ZengTermedia Publishing HouseFolia Neuropathologica1641-46401509-572X2024-06-01631111810.5114/fn.2024.14056954271Neuropathological findings in essential tremorIoannis MavroudisFoivos PetridisEssential tremor (ET) is one of the most common neurological conditions and the most common movement disorder. The pathophysiological mechanisms that underlie this entity have not yet been described. However, recent post-mortem brain studies have provided useful insight into the underlying pathology of ET. Two brain areas have been consistently found to present neuropathological alterations in patients with ET: the brainstem, for presence of Lewy bodies or neuronal depletion, and the cerebellum, regarding Purkinje cells’ morphology and density. In the present study we aim to review the literature on the main neuropathological findings in ET brains.https://www.termedia.pl/Neuropathological-findings-in-essential-tremor,20,54271,1,1.htmlessential tremor neuropathology purkinje cells locus coeruleus lewy bodies |
| spellingShingle | Ioannis Mavroudis Foivos Petridis Neuropathological findings in essential tremor Folia Neuropathologica essential tremor neuropathology purkinje cells locus coeruleus lewy bodies |
| title | Neuropathological findings in essential tremor |
| title_full | Neuropathological findings in essential tremor |
| title_fullStr | Neuropathological findings in essential tremor |
| title_full_unstemmed | Neuropathological findings in essential tremor |
| title_short | Neuropathological findings in essential tremor |
| title_sort | neuropathological findings in essential tremor |
| topic | essential tremor neuropathology purkinje cells locus coeruleus lewy bodies |
| url | https://www.termedia.pl/Neuropathological-findings-in-essential-tremor,20,54271,1,1.html |
| work_keys_str_mv | AT ioannismavroudis neuropathologicalfindingsinessentialtremor AT foivospetridis neuropathologicalfindingsinessentialtremor |