Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing
The cardiopulmonary exercise test (CPET) is an important physiological investigation that can aid clinicians in their evaluation of exercise intolerance and dyspnea. Maximal oxygen consumption (V˙O2max) is the gold-standard measure of aerobic fitness and is determined by the variables that define ox...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/824091 |
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| author | Michael K. Stickland Scott J. Butcher Darcy D. Marciniuk Mohit Bhutani |
| author_facet | Michael K. Stickland Scott J. Butcher Darcy D. Marciniuk Mohit Bhutani |
| author_sort | Michael K. Stickland |
| collection | DOAJ |
| description | The cardiopulmonary exercise test (CPET) is an important physiological investigation that can aid clinicians in their evaluation of exercise intolerance and dyspnea. Maximal oxygen consumption (V˙O2max) is the gold-standard measure of aerobic fitness and is determined by the variables that define oxygen delivery in the Fick equation (V˙O2 = cardiac output × arterial-venous O2 content difference). In healthy subjects, of the variables involved in oxygen delivery, it is the limitations of the cardiovascular system that are most responsible for limiting exercise, as ventilation and gas exchange are sufficient to maintain arterial O2 content up to peak exercise. Patients with lung disease can develop a pulmonary limitation to exercise which can contribute to exercise intolerance and dyspnea. In these patients, ventilation may be insufficient for metabolic demand, as demonstrated by an inadequate breathing reserve, expiratory flow limitation, dynamic hyperinflation, and/or retention of arterial CO2. Lung disease patients can also develop gas exchange impairments with exercise as demonstrated by an increased alveolar-to-arterial O2 pressure difference. CPET testing data, when combined with other clinical/investigation studies, can provide the clinician with an objective method to evaluate cardiopulmonary physiology and determination of exercise intolerance. |
| format | Article |
| id | doaj-art-7f51d91359344c41b949f56d016f0fdf |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-7f51d91359344c41b949f56d016f0fdf2025-02-03T05:51:41ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/824091824091Assessing Exercise Limitation Using Cardiopulmonary Exercise TestingMichael K. Stickland0Scott J. Butcher1Darcy D. Marciniuk2Mohit Bhutani3Pulmonary Division, Department of Medicine, 8334B Aberhart Centre, University of Alberta, Edmonton, AB, T6G 2B7, CanadaSchool of Physical Therapy, University of Saskatchewan, Saskatoon, SK, CanadaDivision of Respiratory, Critical Care and Sleep Medicine and Airways Research Group, University of Saskatchewan, Saskatoon, SK, CanadaPulmonary Division, Department of Medicine, 8334B Aberhart Centre, University of Alberta, Edmonton, AB, T6G 2B7, CanadaThe cardiopulmonary exercise test (CPET) is an important physiological investigation that can aid clinicians in their evaluation of exercise intolerance and dyspnea. Maximal oxygen consumption (V˙O2max) is the gold-standard measure of aerobic fitness and is determined by the variables that define oxygen delivery in the Fick equation (V˙O2 = cardiac output × arterial-venous O2 content difference). In healthy subjects, of the variables involved in oxygen delivery, it is the limitations of the cardiovascular system that are most responsible for limiting exercise, as ventilation and gas exchange are sufficient to maintain arterial O2 content up to peak exercise. Patients with lung disease can develop a pulmonary limitation to exercise which can contribute to exercise intolerance and dyspnea. In these patients, ventilation may be insufficient for metabolic demand, as demonstrated by an inadequate breathing reserve, expiratory flow limitation, dynamic hyperinflation, and/or retention of arterial CO2. Lung disease patients can also develop gas exchange impairments with exercise as demonstrated by an increased alveolar-to-arterial O2 pressure difference. CPET testing data, when combined with other clinical/investigation studies, can provide the clinician with an objective method to evaluate cardiopulmonary physiology and determination of exercise intolerance.http://dx.doi.org/10.1155/2012/824091 |
| spellingShingle | Michael K. Stickland Scott J. Butcher Darcy D. Marciniuk Mohit Bhutani Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing Pulmonary Medicine |
| title | Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing |
| title_full | Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing |
| title_fullStr | Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing |
| title_full_unstemmed | Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing |
| title_short | Assessing Exercise Limitation Using Cardiopulmonary Exercise Testing |
| title_sort | assessing exercise limitation using cardiopulmonary exercise testing |
| url | http://dx.doi.org/10.1155/2012/824091 |
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