Safety, immunogenicity, and protective efficacy of the intranasal live pertussis vaccine GamLPV in an infant monkey model (<i>Papio hamadryas</i>)

Safety, immunogenicity, and protective efficacy of the intranasal live pertussis vaccine GamLPV in an infant monkey model (<i>Papio hamadryas</i>)

INTRODUCTION. The current progressive increase in pertussis incidence and infant mortality rates is due to the insufficient effectiveness of existing vaccines, both in Russia and worldwide. Previous clinical trials showed that healthy adult volunteers developed long-term antibacterial immunity after...

Full description

Saved in:
Bibliographic Details
Main Authors: D. T. Kubrava, A. Yu. Medkova, A. Z. Matua, I. G. Kondzariya, A. A. Amichba, Kh. Z. Trapsh, L. V. Gamgiya, S. G. Kulikov, L. N. Sinyashina, Z. Ya. Mikvabiya, G. I. Karataev
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-12-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
pertussis
live pertussis vaccine
intranasal administration
monkeys
hamadryas baboons
papio hamadryas
experimental model
immunogenicity
safety
protective efficacy
Online Access:https://www.biopreparations.ru/jour/article/view/596
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items