Identification and validation of integrated stress-response-related genes as biomarkers for age-related macular degeneration

Identification and validation of integrated stress-response-related genes as biomarkers for age-related macular degeneration

BackgroundAge-related macular degeneration (AMD) is a prevalent ocular condition associated with aging, serving as a significant contributor to vision loss among middle-aged and older individuals. Studies have shown that AMD and integrated stress response (ISR) are associated with oxidative stress,...

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Bibliographic Details
Main Authors: Jingyi Niu, Ling Jin, Yijun Hu, Yiting Wang, Xiaoning Hao, Wenwen Geng, Ruirui Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
age-related macular degeneration
biomarkers
integrated stress response
SLFN11
Grin1
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1583237/full
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