Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States

Background Cerebrovascular diseases are a major cause of morbidity and mortality worldwide and are the fifth leading cause of death in the United States. Understanding demographic differences in mortality rate trends can raise awareness of demographic disparities. We sought to investigate age‐adjust...

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Main Authors: Sishir Doddi, Nicholas D. Henkel, Oscar Salichs, Richard Burgess, Taryn Hibshman, Jonathan Wright, Isa Malik, Sami Al Kasab, Mouhammad A. Jumaa
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Stroke: Vascular and Interventional Neurology
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Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.123.001158
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author Sishir Doddi
Nicholas D. Henkel
Oscar Salichs
Richard Burgess
Taryn Hibshman
Jonathan Wright
Isa Malik
Sami Al Kasab
Mouhammad A. Jumaa
author_facet Sishir Doddi
Nicholas D. Henkel
Oscar Salichs
Richard Burgess
Taryn Hibshman
Jonathan Wright
Isa Malik
Sami Al Kasab
Mouhammad A. Jumaa
author_sort Sishir Doddi
collection DOAJ
description Background Cerebrovascular diseases are a major cause of morbidity and mortality worldwide and are the fifth leading cause of death in the United States. Understanding demographic differences in mortality rate trends can raise awareness of demographic disparities. We sought to investigate age‐adjusted mortality trends due to cerebrovascular diseases and ischemic stroke for demographic disparities in trend from 1999 to 2020. Methods We used the publicly accessible Centers for Disease Control and Prevention Wide‐Ranging Online Data for Epidemiologic Research database to gather mortality data to determine trends in cerebrovascular diseases and cerebral infarction mortality in the United States from 1999 to 2020. Using the Joinpoint program, temporal trends for cerebrovascular diseases and cerebral infarction mortality were calculated for each demographic group and reported as both annual percentage changes (APCs) or average APC from 1999 to 2020. In addition, trends were compared between groups for significant differences. Results We found an overall decrease in mortality rate for cerebrovascular diseases with average APC −1.9%. In 2020, age‐adjusted mortality rates due to cerebrovascular diseases in the Black population was 1031 per 1 000 000 compared with 679 in the White population. Similarly in 2020, cerebral infarction for the Black population had an age‐adjusted mortality rate of 256.3 compared with the White population's 170.4. When assessing overall trends by race and ethnic group: American Indian/Alaska Native had average APC −2.5%, Asian Pacific Americans had 2.4%, White population had −1.9%, and the Black population had −1.8%. We found a statistically significant difference in trend of decline between the Black and White population cerebrovascular diseases age‐adjusted mortality rates. No significant average APCs were found for cerebral infarction. The results of this study showcase disparities in cerebrovascular diseases mortality in the United States and where additional effort, research, and care should be focused. Conclusion The results of this study showcase disparities in mortality in the United States and where additional effort, research, and care should be focused.
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spelling doaj-art-7f2c4bd6d8bb405c996dd57343b77acd2025-08-20T02:02:50ZengWileyStroke: Vascular and Interventional Neurology2694-57462024-07-014410.1161/SVIN.123.001158Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United StatesSishir Doddi0Nicholas D. Henkel1Oscar Salichs2Richard Burgess3Taryn Hibshman4Jonathan Wright5Isa Malik6Sami Al Kasab7Mouhammad A. Jumaa8University of Toledo College of Medicine Toledo OHUniversity of Toledo College of Medicine Toledo OHUniversity of Toledo College of Medicine Toledo OHDepartment of Neurology ProMedica Neurosciences Institute Toledo OHUniversity of Toledo College of Medicine Toledo OHCollege of Medicine The Ohio State University Columbus OHUniversity of Toledo College of Medicine Toledo OHMedical University of South Carolina Charleston SCDepartment of Neurology ProMedica Neurosciences Institute Toledo OHBackground Cerebrovascular diseases are a major cause of morbidity and mortality worldwide and are the fifth leading cause of death in the United States. Understanding demographic differences in mortality rate trends can raise awareness of demographic disparities. We sought to investigate age‐adjusted mortality trends due to cerebrovascular diseases and ischemic stroke for demographic disparities in trend from 1999 to 2020. Methods We used the publicly accessible Centers for Disease Control and Prevention Wide‐Ranging Online Data for Epidemiologic Research database to gather mortality data to determine trends in cerebrovascular diseases and cerebral infarction mortality in the United States from 1999 to 2020. Using the Joinpoint program, temporal trends for cerebrovascular diseases and cerebral infarction mortality were calculated for each demographic group and reported as both annual percentage changes (APCs) or average APC from 1999 to 2020. In addition, trends were compared between groups for significant differences. Results We found an overall decrease in mortality rate for cerebrovascular diseases with average APC −1.9%. In 2020, age‐adjusted mortality rates due to cerebrovascular diseases in the Black population was 1031 per 1 000 000 compared with 679 in the White population. Similarly in 2020, cerebral infarction for the Black population had an age‐adjusted mortality rate of 256.3 compared with the White population's 170.4. When assessing overall trends by race and ethnic group: American Indian/Alaska Native had average APC −2.5%, Asian Pacific Americans had 2.4%, White population had −1.9%, and the Black population had −1.8%. We found a statistically significant difference in trend of decline between the Black and White population cerebrovascular diseases age‐adjusted mortality rates. No significant average APCs were found for cerebral infarction. The results of this study showcase disparities in cerebrovascular diseases mortality in the United States and where additional effort, research, and care should be focused. Conclusion The results of this study showcase disparities in mortality in the United States and where additional effort, research, and care should be focused.https://www.ahajournals.org/doi/10.1161/SVIN.123.001158demographicsdisparitiesmortalitystroke
spellingShingle Sishir Doddi
Nicholas D. Henkel
Oscar Salichs
Richard Burgess
Taryn Hibshman
Jonathan Wright
Isa Malik
Sami Al Kasab
Mouhammad A. Jumaa
Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
Stroke: Vascular and Interventional Neurology
demographics
disparities
mortality
stroke
title Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
title_full Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
title_fullStr Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
title_full_unstemmed Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
title_short Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States
title_sort disparities of mortality trends due to cerebrovascular diseases and cerebrovascular infarction in the united states
topic demographics
disparities
mortality
stroke
url https://www.ahajournals.org/doi/10.1161/SVIN.123.001158
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