Miniaturized lensless microfluidic on-chip bio-imaging detection

The conventional high-resolution optical microscopy for biomedical imaging has high cost and low portability due to bulky optical lenses system.To realize miniaturized imaging,the recent advance of lensless microfluidic on-chip imaging technique based on the integration of CMOS image sensor and micr...

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Main Authors: Jin CHEN, Xiwei HUANG, Yangbo LI, Jixuan LIU, Lingling SUN
Format: Article
Language:zho
Published: China InfoCom Media Group 2019-06-01
Series:物联网学报
Subjects:
Online Access:http://www.wlwxb.com.cn/thesisDetails#10.11959/j.issn.2096-3750.2019.00111
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author Jin CHEN
Xiwei HUANG
Yangbo LI
Jixuan LIU
Lingling SUN
author_facet Jin CHEN
Xiwei HUANG
Yangbo LI
Jixuan LIU
Lingling SUN
author_sort Jin CHEN
collection DOAJ
description The conventional high-resolution optical microscopy for biomedical imaging has high cost and low portability due to bulky optical lenses system.To realize miniaturized imaging,the recent advance of lensless microfluidic on-chip imaging technique based on the integration of CMOS image sensor and microfluidics has provided one promising solution.Therefore,the architecture,principle,problems and improvement solutions for different miniaturized lensless microfluidic on-chip bio-imaging,including shadow imaging,holographic imaging,fluorescent imaging and color imaging were reviewed.And the deficiencies and possible development directions were discussed.
format Article
id doaj-art-7f2a5c3a4164491ea9bdcb86e2cce166
institution OA Journals
issn 2096-3750
language zho
publishDate 2019-06-01
publisher China InfoCom Media Group
record_format Article
series 物联网学报
spelling doaj-art-7f2a5c3a4164491ea9bdcb86e2cce1662025-08-20T02:09:14ZzhoChina InfoCom Media Group物联网学报2096-37502019-06-01391959644415Miniaturized lensless microfluidic on-chip bio-imaging detectionJin CHENXiwei HUANGYangbo LIJixuan LIULingling SUNThe conventional high-resolution optical microscopy for biomedical imaging has high cost and low portability due to bulky optical lenses system.To realize miniaturized imaging,the recent advance of lensless microfluidic on-chip imaging technique based on the integration of CMOS image sensor and microfluidics has provided one promising solution.Therefore,the architecture,principle,problems and improvement solutions for different miniaturized lensless microfluidic on-chip bio-imaging,including shadow imaging,holographic imaging,fluorescent imaging and color imaging were reviewed.And the deficiencies and possible development directions were discussed.http://www.wlwxb.com.cn/thesisDetails#10.11959/j.issn.2096-3750.2019.00111on-chip imaging;lensless;microfluidic;CMOS image sensor;miniaturization
spellingShingle Jin CHEN
Xiwei HUANG
Yangbo LI
Jixuan LIU
Lingling SUN
Miniaturized lensless microfluidic on-chip bio-imaging detection
物联网学报
on-chip imaging;lensless;microfluidic;CMOS image sensor;miniaturization
title Miniaturized lensless microfluidic on-chip bio-imaging detection
title_full Miniaturized lensless microfluidic on-chip bio-imaging detection
title_fullStr Miniaturized lensless microfluidic on-chip bio-imaging detection
title_full_unstemmed Miniaturized lensless microfluidic on-chip bio-imaging detection
title_short Miniaturized lensless microfluidic on-chip bio-imaging detection
title_sort miniaturized lensless microfluidic on chip bio imaging detection
topic on-chip imaging;lensless;microfluidic;CMOS image sensor;miniaturization
url http://www.wlwxb.com.cn/thesisDetails#10.11959/j.issn.2096-3750.2019.00111
work_keys_str_mv AT jinchen miniaturizedlenslessmicrofluidiconchipbioimagingdetection
AT xiweihuang miniaturizedlenslessmicrofluidiconchipbioimagingdetection
AT yangboli miniaturizedlenslessmicrofluidiconchipbioimagingdetection
AT jixuanliu miniaturizedlenslessmicrofluidiconchipbioimagingdetection
AT linglingsun miniaturizedlenslessmicrofluidiconchipbioimagingdetection