Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis
The presence of an opportunistic infection in a patient in sub-Saharan Africa is assumed to be due to underlying immunosuppression from human immunodeficiency virus (HIV) infection. The presence of disseminated cryptococcosis in a non-HIV-infected patient is interesting as it is unique in our setti...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2010-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/813 |
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| author | Mohammed Mitha Preneshni Naicker Prakash Mahida |
| author_facet | Mohammed Mitha Preneshni Naicker Prakash Mahida |
| author_sort | Mohammed Mitha |
| collection | DOAJ |
| description |
The presence of an opportunistic infection in a patient in sub-Saharan Africa is assumed to be due to underlying immunosuppression from human immunodeficiency virus (HIV) infection. The presence of disseminated cryptococcosis in a non-HIV-infected patient is interesting as it is unique in our setting because the majority of infections are found in HIV-infected individuals. The protean manifestations of the disease and its predilection for immunosuppressed patients make cryptococcosis a challenging and elusive disease to diagnose in HIV-negative patients in our setting, especially due to limited resources. We present a case of disseminated cryptococcosis in an immunocompetent patient and discuss diagnostic and therapeutic features in this subset of patients.
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| format | Article |
| id | doaj-art-7f219f19c13144b2a00d581ff676ca10 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2010-05-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-7f219f19c13144b2a00d581ff676ca102025-08-20T02:57:01ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802010-05-0140810.3855/jidc.813Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosisMohammed Mitha0Preneshni Naicker1Prakash Mahida2Tygerberg Hospital, University of Stellenbosch, Cape Town, South AfricaTygerberg Hospital, University of Stellenbosch, Cape Town, South AfricaTygerberg Hospital, University of Stellenbosch, Cape Town, South Africa The presence of an opportunistic infection in a patient in sub-Saharan Africa is assumed to be due to underlying immunosuppression from human immunodeficiency virus (HIV) infection. The presence of disseminated cryptococcosis in a non-HIV-infected patient is interesting as it is unique in our setting because the majority of infections are found in HIV-infected individuals. The protean manifestations of the disease and its predilection for immunosuppressed patients make cryptococcosis a challenging and elusive disease to diagnose in HIV-negative patients in our setting, especially due to limited resources. We present a case of disseminated cryptococcosis in an immunocompetent patient and discuss diagnostic and therapeutic features in this subset of patients. https://jidc.org/index.php/journal/article/view/813Disseminated cryptococcusHIV negativeSouth Africa |
| spellingShingle | Mohammed Mitha Preneshni Naicker Prakash Mahida Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis Journal of Infection in Developing Countries Disseminated cryptococcus HIV negative South Africa |
| title | Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis |
| title_full | Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis |
| title_fullStr | Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis |
| title_full_unstemmed | Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis |
| title_short | Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis |
| title_sort | disseminated cryptococcosis in an hiv negative patient in south africa the elusive differential diagnosis |
| topic | Disseminated cryptococcus HIV negative South Africa |
| url | https://jidc.org/index.php/journal/article/view/813 |
| work_keys_str_mv | AT mohammedmitha disseminatedcryptococcosisinanhivnegativepatientinsouthafricatheelusivedifferentialdiagnosis AT preneshninaicker disseminatedcryptococcosisinanhivnegativepatientinsouthafricatheelusivedifferentialdiagnosis AT prakashmahida disseminatedcryptococcosisinanhivnegativepatientinsouthafricatheelusivedifferentialdiagnosis |