Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

Chronic obstructive lung disease determines morbidity and mortality of patients with cystic fibrosis (CF). CF airways are characterized by a nonresolving neutrophilic inflammation. After pathogen contact or prolonged activation, neutrophils release DNA fibres decorated with antimicrobial proteins, f...

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Main Authors:	Veronica Marcos, Zhe Zhou-Suckow, Ali Önder Yildirim, Alexander Bohla, Andreas Hector, Ljubomir Vitkov, Wolf Dietrich Krautgartner, Walter Stoiber, Matthias Griese, Oliver Eickelberg, Marcus A. Mall, Dominik Hartl
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2015/408935
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