Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis
Extended spectrum beta-lactamases (ESBL) produced by Gram-negative uropathogens constitute an emerging public-health concern. The aim of the study was to determine the prevalence of ESBL producing enterobacteriaceae uropathogens in Sokoto. The study was undertaken at Specialist Hospital Sokoto (SHS)...
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| Language: | English |
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Hammer Head Production Limited
2017-06-01
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| Series: | Sokoto Journal of Medical Laboratory Science |
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| Online Access: | https://sokjmls.com.ng/index.php/SJMLS/article/view/346 |
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| author | Nuhu Tanko *, Chado Jibril Baba, Olowookere Ahmed, Hussain Ungokore Yahaya, Nura Umar Muhammad |
| author_facet | Nuhu Tanko *, Chado Jibril Baba, Olowookere Ahmed, Hussain Ungokore Yahaya, Nura Umar Muhammad |
| author_sort | Nuhu Tanko *, Chado Jibril Baba, Olowookere Ahmed, Hussain Ungokore Yahaya, Nura Umar Muhammad |
| collection | DOAJ |
| description | Extended spectrum beta-lactamases (ESBL) produced by Gram-negative uropathogens constitute an emerging public-health concern. The aim of the study was to determine the prevalence of ESBL producing enterobacteriaceae uropathogens in Sokoto. The study was undertaken at Specialist Hospital Sokoto (SHS) over a 2-month period. Ninety-one urine samples were collected. The isolates collected were identified using biochemical tests. All isolates were tested for susceptibility to eight different antibiotics by the modified Kirby Baeur disc diffusion. Screening and confirmatory tests for ESBL production were done according to Clinical Laboratory Standard Institute (CLSI) guidelines. A total of 25 isolates were Gram-negative which accounted for 41% prevalence, while 59% accounted for Gram-positive. E. coli was the most common isolates (44%), followed by Proteus mirabilis (20%), Klebsiella spp (16%), Enterobacter spp (12%), and Salmonella spp (8%). All isolates displayed multi-drug resistance. The overall production of ESBL-producing isolates was 16%. Our study confirms the prevalence of ESBL-producing uropathogens in Sokoto. |
| format | Article |
| id | doaj-art-7f196bfba0f94bac8b6160cae3dc6a52 |
| institution | Kabale University |
| issn | 2536-7153 |
| language | English |
| publishDate | 2017-06-01 |
| publisher | Hammer Head Production Limited |
| record_format | Article |
| series | Sokoto Journal of Medical Laboratory Science |
| spelling | doaj-art-7f196bfba0f94bac8b6160cae3dc6a522025-08-20T03:41:46ZengHammer Head Production LimitedSokoto Journal of Medical Laboratory Science2536-71532017-06-0122346Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto MetropolisNuhu Tanko *, Chado Jibril Baba, Olowookere Ahmed, Hussain Ungokore Yahaya, Nura Umar MuhammadExtended spectrum beta-lactamases (ESBL) produced by Gram-negative uropathogens constitute an emerging public-health concern. The aim of the study was to determine the prevalence of ESBL producing enterobacteriaceae uropathogens in Sokoto. The study was undertaken at Specialist Hospital Sokoto (SHS) over a 2-month period. Ninety-one urine samples were collected. The isolates collected were identified using biochemical tests. All isolates were tested for susceptibility to eight different antibiotics by the modified Kirby Baeur disc diffusion. Screening and confirmatory tests for ESBL production were done according to Clinical Laboratory Standard Institute (CLSI) guidelines. A total of 25 isolates were Gram-negative which accounted for 41% prevalence, while 59% accounted for Gram-positive. E. coli was the most common isolates (44%), followed by Proteus mirabilis (20%), Klebsiella spp (16%), Enterobacter spp (12%), and Salmonella spp (8%). All isolates displayed multi-drug resistance. The overall production of ESBL-producing isolates was 16%. Our study confirms the prevalence of ESBL-producing uropathogens in Sokoto.https://sokjmls.com.ng/index.php/SJMLS/article/view/346phenotypic detection, esbl, uropathogens |
| spellingShingle | Nuhu Tanko *, Chado Jibril Baba, Olowookere Ahmed, Hussain Ungokore Yahaya, Nura Umar Muhammad Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis Sokoto Journal of Medical Laboratory Science phenotypic detection, esbl, uropathogens |
| title | Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis |
| title_full | Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis |
| title_fullStr | Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis |
| title_full_unstemmed | Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis |
| title_short | Phenotypic Detection of Extended Spectrum Beta-Lactamase (ESBL) Produced by Gram-Negative Uropathogens in Sokoto Metropolis |
| title_sort | phenotypic detection of extended spectrum beta lactamase esbl produced by gram negative uropathogens in sokoto metropolis |
| topic | phenotypic detection, esbl, uropathogens |
| url | https://sokjmls.com.ng/index.php/SJMLS/article/view/346 |
| work_keys_str_mv | AT nuhutankochadojibrilbabaolowookereahmedhussainungokoreyahayanuraumarmuhammad phenotypicdetectionofextendedspectrumbetalactamaseesblproducedbygramnegativeuropathogensinsokotometropolis |