Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period?
Introduction: Healthcare-associated infections (HAIs) are common in intensive care unit (ICU) patients and may cause devastating consequences. However, the prevalence of HAI and its effects on in-hospital mortality among critically ill COVID-19 patients is ambiguous. We determined the prevalence of...
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The Journal of Infection in Developing Countries
2024-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/19548 |
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| author | İhsan Solmaz Şeyhmus Kavak Songül Araç Hakan Akelma Bilgin Bahadır Başgöz Sedrettin Koyun Şafak Kaya |
| author_facet | İhsan Solmaz Şeyhmus Kavak Songül Araç Hakan Akelma Bilgin Bahadır Başgöz Sedrettin Koyun Şafak Kaya |
| author_sort | İhsan Solmaz |
| collection | DOAJ |
| description |
Introduction: Healthcare-associated infections (HAIs) are common in intensive care unit (ICU) patients and may cause devastating consequences. However, the prevalence of HAI and its effects on in-hospital mortality among critically ill COVID-19 patients is ambiguous. We determined the prevalence of HAI and the rate of mortality in critically ill COVID-19 patients and compared it with pre-pandemic ICU patients.
Methodology: This retrospective study was conducted with adult ICU patients admitted to Gazi Yaşargil Training and Research Hospital (Diyarbakir,Turkey) in April-November 2019 (defined as the pre-pandemic period) and in April-November 2020 (defined as the pandemic period). All patients in the pandemic period had COVID-19, while none in the pre-pandemic period did. Patients diagnosed with HAIs during the in-hospital follow-up period were recorded.
Results: Of 4596 enrollees, 3386 (73.7%) were pandemic-period patients and 1210 (26.3%) were pre-pandemic-period patients. HAI prevalence was significantly higher at 5.9% (n = 71) in the pandemic-period patients and 2.7% (n = 91) in the pre-pandemic-period patients (p < 0.001). Comorbidities including hypertension (63.4% vs 14.2%, p < 0.001), diabetes mellitus (39.4% vs 8.8%, p < 0.001), and coronary artery disease (30.9% vs 10.9%, p = 0.002) were significantly more frequent in pandemic-period HAI-positive patients. The most common HAI was catheter-related bloodstream infection in both groups, with similar frequency (p = 0.652). In-hospital mortality rate was 85.9% versus 65.9% in pandemic- versus pre-pandemic-period HAI-positive patients (p < 0,05).
Conclusions: The prevalence of HAI and the in-hospital mortality rate was significantly higher among pandemic-period patients.
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| format | Article |
| id | doaj-art-7f17f238b03c44829261a03324976f69 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-7f17f238b03c44829261a03324976f692025-08-20T02:57:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-09-011809.110.3855/jidc.19548Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period?İhsan Solmaz0Şeyhmus Kavak1Songül Araç2Hakan Akelma3Bilgin Bahadır Başgöz4Sedrettin Koyun5Şafak Kaya6Department of Internal Medicine, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, TurkeyDepartment of Radiology, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey Department of Emergency, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, TurkeyDepartment of Anesthesia and Reanimation, University of Artuklu, Mardin Training and Research Hospital, Mardin, Turkey Department of Internal Medicine, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, TurkeyDepartment of Internal Medicine, Kızıltepe State Hospital, Mardin, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey Introduction: Healthcare-associated infections (HAIs) are common in intensive care unit (ICU) patients and may cause devastating consequences. However, the prevalence of HAI and its effects on in-hospital mortality among critically ill COVID-19 patients is ambiguous. We determined the prevalence of HAI and the rate of mortality in critically ill COVID-19 patients and compared it with pre-pandemic ICU patients. Methodology: This retrospective study was conducted with adult ICU patients admitted to Gazi Yaşargil Training and Research Hospital (Diyarbakir,Turkey) in April-November 2019 (defined as the pre-pandemic period) and in April-November 2020 (defined as the pandemic period). All patients in the pandemic period had COVID-19, while none in the pre-pandemic period did. Patients diagnosed with HAIs during the in-hospital follow-up period were recorded. Results: Of 4596 enrollees, 3386 (73.7%) were pandemic-period patients and 1210 (26.3%) were pre-pandemic-period patients. HAI prevalence was significantly higher at 5.9% (n = 71) in the pandemic-period patients and 2.7% (n = 91) in the pre-pandemic-period patients (p < 0.001). Comorbidities including hypertension (63.4% vs 14.2%, p < 0.001), diabetes mellitus (39.4% vs 8.8%, p < 0.001), and coronary artery disease (30.9% vs 10.9%, p = 0.002) were significantly more frequent in pandemic-period HAI-positive patients. The most common HAI was catheter-related bloodstream infection in both groups, with similar frequency (p = 0.652). In-hospital mortality rate was 85.9% versus 65.9% in pandemic- versus pre-pandemic-period HAI-positive patients (p < 0,05). Conclusions: The prevalence of HAI and the in-hospital mortality rate was significantly higher among pandemic-period patients. https://jidc.org/index.php/journal/article/view/19548Healthcare-associated infectionsintensive care unitsCOVID-19 |
| spellingShingle | İhsan Solmaz Şeyhmus Kavak Songül Araç Hakan Akelma Bilgin Bahadır Başgöz Sedrettin Koyun Şafak Kaya Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? Journal of Infection in Developing Countries Healthcare-associated infections intensive care units COVID-19 |
| title | Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? |
| title_full | Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? |
| title_fullStr | Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? |
| title_full_unstemmed | Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? |
| title_short | Healthcare-associated infections in patients with COVID-19: is it different from the pre-pandemic period? |
| title_sort | healthcare associated infections in patients with covid 19 is it different from the pre pandemic period |
| topic | Healthcare-associated infections intensive care units COVID-19 |
| url | https://jidc.org/index.php/journal/article/view/19548 |
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