Recent Developments in Ventricular Assist Device Therapy

The evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for L...

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Main Authors: Angel Moctezuma-Ramirez, Haseeb Mohammed, Austin Hughes, Abdelmotagaly Elgalad
Format: Article
Language:English
Published: IMR Press 2025-01-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25440
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author Angel Moctezuma-Ramirez
Haseeb Mohammed
Austin Hughes
Abdelmotagaly Elgalad
author_facet Angel Moctezuma-Ramirez
Haseeb Mohammed
Austin Hughes
Abdelmotagaly Elgalad
author_sort Angel Moctezuma-Ramirez
collection DOAJ
description The evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for LVAD recipients. Innovations in wireless power transfer technologies aim to mitigate driveline-related complications, enhancing patient safety and quality of life. Pediatric ventricular assist devices (VADs) remain a critical unmet need; challenges in developing pediatric VADs include device sizing and managing congenital heart disease. Advances in LVAD technology adapted for use in right ventricular assist devices (RVADs) make possible the effective management of right ventricular failure in patients with acute cardiac conditions or congenital heart defects. To address disparities in mechanical circulatory support (MCS) access, cost-effective VAD designs have been developed internationally. The Vitalmex device from Mexico City combines pulsatile-flow technology with a paracorporeal design, utilizing cost-effective materials like silicone-elastic and titanium, and features a reusable pump housing to minimize manufacturing and operational costs. Romanian researchers have used advanced mathematical modeling and three-dimensional (3D) printing to produce a rim-driven, hubless axial-flow pump, achieving efficient blood flow with a compact design that includes a wireless power supply to reduce infection risk. In conclusion, MCS continues to advance with technological innovation and global collaboration. Ongoing efforts are essential to optimize outcomes, expand indications, and improve access to life-saving therapies worldwide.
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spelling doaj-art-7f16d23a3c5043a0b41aaca0cfe3a0512025-01-25T10:41:20ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-01-012612544010.31083/RCM25440S1530-6550(24)01624-7Recent Developments in Ventricular Assist Device TherapyAngel Moctezuma-Ramirez0Haseeb Mohammed1Austin Hughes2Abdelmotagaly Elgalad3Center for Preclinical Surgical & Interventional Research, The Texas Heart Institute, Houston, TX 77030, USATexas A&M School of Medicine, Bryan, TX 77843, USAThe University of Texas Health Science Center at Houston, Houston, TX 77054, USACenter for Preclinical Surgical & Interventional Research, The Texas Heart Institute, Houston, TX 77030, USAThe evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for LVAD recipients. Innovations in wireless power transfer technologies aim to mitigate driveline-related complications, enhancing patient safety and quality of life. Pediatric ventricular assist devices (VADs) remain a critical unmet need; challenges in developing pediatric VADs include device sizing and managing congenital heart disease. Advances in LVAD technology adapted for use in right ventricular assist devices (RVADs) make possible the effective management of right ventricular failure in patients with acute cardiac conditions or congenital heart defects. To address disparities in mechanical circulatory support (MCS) access, cost-effective VAD designs have been developed internationally. The Vitalmex device from Mexico City combines pulsatile-flow technology with a paracorporeal design, utilizing cost-effective materials like silicone-elastic and titanium, and features a reusable pump housing to minimize manufacturing and operational costs. Romanian researchers have used advanced mathematical modeling and three-dimensional (3D) printing to produce a rim-driven, hubless axial-flow pump, achieving efficient blood flow with a compact design that includes a wireless power supply to reduce infection risk. In conclusion, MCS continues to advance with technological innovation and global collaboration. Ongoing efforts are essential to optimize outcomes, expand indications, and improve access to life-saving therapies worldwide.https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25440lvadminimally invasive surgerypediatric vadrvad supportwireless lvadcost-effective vad
spellingShingle Angel Moctezuma-Ramirez
Haseeb Mohammed
Austin Hughes
Abdelmotagaly Elgalad
Recent Developments in Ventricular Assist Device Therapy
Reviews in Cardiovascular Medicine
lvad
minimally invasive surgery
pediatric vad
rvad support
wireless lvad
cost-effective vad
title Recent Developments in Ventricular Assist Device Therapy
title_full Recent Developments in Ventricular Assist Device Therapy
title_fullStr Recent Developments in Ventricular Assist Device Therapy
title_full_unstemmed Recent Developments in Ventricular Assist Device Therapy
title_short Recent Developments in Ventricular Assist Device Therapy
title_sort recent developments in ventricular assist device therapy
topic lvad
minimally invasive surgery
pediatric vad
rvad support
wireless lvad
cost-effective vad
url https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25440
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AT haseebmohammed recentdevelopmentsinventricularassistdevicetherapy
AT austinhughes recentdevelopmentsinventricularassistdevicetherapy
AT abdelmotagalyelgalad recentdevelopmentsinventricularassistdevicetherapy