Comprehensive Analysis of TCR and BCR Repertoires: Insights into Methodologies, Challenges, and Applications
Abstract The diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) underpins the adaptive immune system’s ability to recognize and respond to a wide array of antigens. Recent advancements in RNA sequencing have expanded its application beyond transcriptomics to include the analysis of imm...
Saved in:
| Main Authors: | Kayoung Seo, Jung Kyoon Choi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2025-02-01
|
| Series: | Genomics & Informatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s44342-024-00034-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Alterations in BCR heavy chain CDR3 repertoire characteristics in pediatric mycoplasma pneumoniae infection
by: Yanfei Chen, et al.
Published: (2025-06-01) -
Exploiting TCR Repertoire Analysis to Select Therapeutic TCRs for Cancer Immunotherapy
by: Ursule M. Demaël, et al.
Published: (2025-08-01) -
Human TCR repertoire in cancer
by: Lin Chen, et al.
Published: (2024-09-01) -
Pre-treatment peripheral blood TCR repertoire as a predictor of response in patients with NSCLC treated with immunochemotherapy
by: Yong Yang, et al.
Published: (2025-07-01) -
The intratumoral landscape of T cell receptor repertoire in esophageal squamous cell carcinoma
by: Meng Yang, et al.
Published: (2024-11-01)