Comprehensive Analysis of TCR and BCR Repertoires: Insights into Methodologies, Challenges, and Applications

Abstract The diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) underpins the adaptive immune system’s ability to recognize and respond to a wide array of antigens. Recent advancements in RNA sequencing have expanded its application beyond transcriptomics to include the analysis of imm...

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Bibliographic Details
Main Authors: Kayoung Seo, Jung Kyoon Choi
Format: Article
Language:English
Published: BioMed Central 2025-02-01
Series:Genomics & Informatics
Subjects:
Online Access:https://doi.org/10.1186/s44342-024-00034-z
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