Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks

The integration of artificial intelligence (AI) in protein design presents unparalleled opportunities for innovation in bioengineering and biotechnology. However, it also raises significant biosecurity concerns. This review examines the changing landscape of bioweapon risks, the dual-use potential o...

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Main Author: Nicole E. Wheeler
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1537471/full
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author Nicole E. Wheeler
author_facet Nicole E. Wheeler
author_sort Nicole E. Wheeler
collection DOAJ
description The integration of artificial intelligence (AI) in protein design presents unparalleled opportunities for innovation in bioengineering and biotechnology. However, it also raises significant biosecurity concerns. This review examines the changing landscape of bioweapon risks, the dual-use potential of AI-driven bioengineering tools, and the necessary safeguards to prevent misuse while fostering innovation. It highlights emerging policy frameworks, technical safeguards, and community responses aimed at mitigating risks and enabling responsible development and application of AI in protein design.
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spelling doaj-art-7f076c243d694cec81060efc3cb600ee2025-02-05T07:32:36ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-02-011310.3389/fbioe.2025.15374711537471Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risksNicole E. WheelerThe integration of artificial intelligence (AI) in protein design presents unparalleled opportunities for innovation in bioengineering and biotechnology. However, it also raises significant biosecurity concerns. This review examines the changing landscape of bioweapon risks, the dual-use potential of AI-driven bioengineering tools, and the necessary safeguards to prevent misuse while fostering innovation. It highlights emerging policy frameworks, technical safeguards, and community responses aimed at mitigating risks and enabling responsible development and application of AI in protein design.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1537471/fullartificial intellegencebiotechnologyAI safetyprotein design and engineeringsynthetic biology
spellingShingle Nicole E. Wheeler
Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
Frontiers in Bioengineering and Biotechnology
artificial intellegence
biotechnology
AI safety
protein design and engineering
synthetic biology
title Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
title_full Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
title_fullStr Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
title_full_unstemmed Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
title_short Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks
title_sort responsible ai in biotechnology balancing discovery innovation and biosecurity risks
topic artificial intellegence
biotechnology
AI safety
protein design and engineering
synthetic biology
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1537471/full
work_keys_str_mv AT nicoleewheeler responsibleaiinbiotechnologybalancingdiscoveryinnovationandbiosecurityrisks