A Novel, Safe, Non-Adjuvanted Alphavirus Replicon-Based Vaccine Expressing the Feline Leukemia Virus Envelope Protein Protects Against Virulent FeLV Challenge

A Novel, Safe, Non-Adjuvanted Alphavirus Replicon-Based Vaccine Expressing the Feline Leukemia Virus Envelope Protein Protects Against Virulent FeLV Challenge

<b>Background/Objectives:</b> A number of different vaccines against feline leukemia virus (FeLV) are available; however, there is continuous debate regarding the efficacy advantages of adjuvanted vaccines versus the potential safety advantages of non-adjuvanted vaccines. <b>Method...

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Bibliographic Details
Main Authors: Kari Carritt, Randall Davis, Ken Stachura, Paige Crumley, Mark Mogler, Madeleine Stahl, Lijuan Deng, Zach Xu, Ian Tarpey
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
feline leukemia virus
RNA particle
envelope protein
vaccine
efficacy
safety
Online Access:https://www.mdpi.com/2076-393X/13/7/697
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