MiR-363-3p induces tamoxifen resistance in breast cancer cells through PTEN modulation

MiR-363-3p induces tamoxifen resistance in breast cancer cells through PTEN modulation

Abstract Nowadays, the investigation for overcoming tamoxifen (TAM) resistance is confronting a considerable challenge. Therefore, immediate attention is required to elucidate the mechanism underlying TAM resistance in breast cancer. This research primarily aimed to define how miRNA-363-3p facilitat...

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Bibliographic Details
Main Authors: Yaning Liang, Cuiyu Shi, Yu Wang, Bingjie Fan, Wei Song, Rong Shen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Hsa-miR-363-3p
Breast cancer
PTEN
TAM resistance
PI3K/AKT signaling pathway
Online Access:https://doi.org/10.1038/s41598-024-83938-8
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